Aims Sirtuins have been implicated in the aging process, however, the functions of SIRT2 in
post-maturation aging of oocytes are not fully understood. The purpose of the present …

Postovulatory oocyte aging has a major influence on the development potential of embryos.
Many antioxidants can delay oocyte aging by regulating the expression of SIRT1. However …

Recent researches have demonstrated that many nanoparticles are harmful to
spermatogenesis. However, the reported nanoparticles-elicited testicular pathologies have …

Background Diminished ovarian reserve (DOR) significantly increases the risk of female
infertility and contributes to reproductive technology failure. Recently, the role of melatonin in …

Diquat is a fast, potent, and widely used bipyridine herbicide in agriculture and it induces
oxidative stress in several animal models. However, its genotoxic effects on the male …

Objective This study examined the in vitro effect of melatonin on the protein synthesis of
mitochondria, as well as autophagy in matured oocytes of aged mice. Materials and …

Prolonged culture of metaphase II oocytes is an in vitro aging process that compromises
oocyte quality. We tested whether melatonin preserves epigenetic modifications in oocytes …

Dynamic epigenetic regulation is critical for proper oogenesis and early embryo
development. During oogenesis, fully grown germinal vesicle oocytes develop to mature …

The main problem in dairy herds is reproductive disorders, which are influenced by many
factors, including temperature. Heat stress reduces the quality of oocytes and their …

Objective. Premature ovarian insufficiency (POI) is a female reproductive disorder of
unknown etiology with no definite pathogenesis. Melatonin (MT) is an endogenous hormone …