Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach

JV Castell, MT Donato, MJ Gómez-Lechón - Experimental and Toxicologic …, 2005 - Elsevier
Lung is a target organ for the toxicity of inhalated compounds. The respiratory tract is
frequently exposed to elevated concentrations of these compounds and become the primary …

Exposure of human lung cells to polystyrene microplastics significantly retards cell proliferation and triggers morphological changes

KE Goodman, JT Hare, ZI Khamis, T Hua… - Chemical research in …, 2021 - ACS Publications
Microplastics in the environment produced by decomposition of globally increasing waste
plastics have become a dominant component of both water and air pollution. To examine the …

[HTML][HTML] Deciphering the code between air pollution and disease: The effect of particulate matter on cancer hallmarks

M Santibáñez-Andrade, YI Chirino… - International journal of …, 2019 - mdpi.com
Air pollution has been recognized as a global health problem, causing around 7 million
deaths worldwide and representing one of the highest environmental crises that we are now …

Exposure to ZnO nanoparticles induces oxidative stress and cytotoxicity in human colon carcinoma cells

B De Berardis, G Civitelli, M Condello, P Lista… - Toxicology and applied …, 2010 - Elsevier
Engineered nanoparticles offer great promise in many industrial and biomedical
applications, however little information is available about gastrointestinal toxicity. The …

Particle size and composition distribution analysis of automotive brake abrasion dusts for the evaluation of antimony sources of airborne particulate matter

A Iijima, K Sato, K Yano, H Tago, M Kato… - Atmospheric …, 2007 - Elsevier
Abrasion dusts from three types of commercially available non-steel brake pads were
generated by a brake dynamometer at disk temperatures of 200, 300 and 400° C. The …

Beijing urban particulate matter-induced injury and inflammation in human lung epithelial cells and the protective effects of fucosterol from Sargassum binderi (Sonder …

IPS Fernando, TU Jayawardena, HS Kim, WW Lee… - Environmental …, 2019 - Elsevier
Particulate matter (PM) air pollution has gradually become a widespread problem in East
Asia. PM may cause unfamiliar inflammatory responses, oxidative stress, and pulmonary …

PM2. 5 exposure-induced autophagy is mediated by lncRNA loc146880 which also promotes the migration and invasion of lung cancer cells

X Deng, N Feng, M Zheng, X Ye, H Lin, X Yu… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Evidence shows that individuals who are under long-term exposure to
environmental PM 2.5 are at increased risk of lung cancer. Various laboratory experiments …

Chemical composition of PM10 and its in vitro toxicological impacts on lung cells during the Middle Eastern Dust (MED) storms in Ahvaz, Iran

A Naimabadi, A Ghadiri, E Idani, AA Babaei… - Environmental …, 2016 - Elsevier
Reports on the effects of PM 10 from dust storm on lung cells are limited. The main purpose
of this study was to investigate the chemical composition and in vitro toxicological impacts of …

Emission factor for antimony in brake abrasion dusts as one of the major atmospheric antimony sources

A Iijima, K Sato, K Yano, M Kato… - … science & technology, 2008 - ACS Publications
Abrasion tests were conducted using a brake dynamometer to determine the antimony (Sb)
emission factor originating from automobiles. Abrasion dusts from commercially available …

Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes

US Gaharwar, R Meena… - Journal of Applied …, 2017 - Wiley Online Library
Over the past few decades nanotechnology and material science has progressed extremely
rapidly. Iron oxide nanoparticles (IONPs) owing to their unique magnetic properties have a …