Cis-regulatory sequences in plants: their importance, discovery, and future challenges

RJ Schmitz, E Grotewold, M Stam - The plant cell, 2022 - academic.oup.com
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

cis-Regulatory Elements in Plant Development, Adaptation, and Evolution

AP Marand, AL Eveland, K Kaufmann… - Annual review of …, 2023 - annualreviews.org
cis-Regulatory elements encode the genomic blueprints that ensure the proper
spatiotemporal patterning of gene expression necessary for appropriate development and …

A cis-regulatory atlas in maize at single-cell resolution

AP Marand, Z Chen, A Gallavotti, RJ Schmitz - Cell, 2021 - cell.com
Summary cis-regulatory elements (CREs) encode the genomic blueprints of spatiotemporal
gene expression programs enabling highly specialized cell functions. Using single-cell …

Machine learning bridges omics sciences and plant breeding

J Yan, X Wang - Trends in Plant Science, 2023 - cell.com
Some of the biological knowledge obtained from fundamental research will be implemented
in applied plant breeding. To bridge basic research and breeding practice, machine learning …

Single-cell transcriptome analysis in plants: advances and challenges

R Shaw, X Tian, J Xu - Molecular Plant, 2021 - cell.com
The rapid and enthusiastic adoption of single-cell RNA sequencing (scRNA-seq) has
demonstrated that this technology is far more than just another way to perform transcriptome …

A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants

R Shahan, CW Hsu, TM Nolan, BJ Cole, IW Taylor… - Developmental cell, 2022 - cell.com
In all multicellular organisms, transcriptional networks orchestrate organ development. The
Arabidopsis root, with its simple structure and indeterminate growth, is an ideal model for …

Advances and opportunities in single-cell transcriptomics for plant research

C Seyfferth, J Renema, JR Wendrich… - Annual Review of …, 2021 - annualreviews.org
Single-cell approaches are quickly changing our view on biological systems by increasing
the spatiotemporal resolution of our analyses to the level of the individual cell. The field of …

Synthetic promoter designs enabled by a comprehensive analysis of plant core promoters

T Jores, J Tonnies, T Wrightsman, ES Buckler… - Nature Plants, 2021 - nature.com
Targeted engineering of plant gene expression holds great promise for ensuring food
security and for producing biopharmaceuticals in plants. However, this engineering requires …

Single-cell transcriptomic analysis reveals the developmental trajectory and transcriptional regulatory networks of pigment glands in Gossypium bickii

Y Sun, Y Han, K Sheng, P Yang, Y Cao, H Li, QH Zhu… - Molecular Plant, 2023 - cell.com
Comprehensive utilization of cottonseeds is limited by the presence of pigment glands and
its inclusion gossypol. The ideal cotton has glandless seeds but a glanded plant, a trait …

Single-cell and spatial multi-omics in the plant sciences: Technical advances, applications, and perspectives

X Yu, Z Liu, X Sun - Plant communications, 2023 - cell.com
Plants contain a large number of cell types and exhibit complex regulatory mechanisms.
Studies at the single-cell level have gradually become more common in plant science …