Targeting the tumor biophysical microenvironment to reduce resistance to immunotherapy

T Zhang, Y Jia, Y Yu, B Zhang, F Xu, H Guo - Advanced drug delivery …, 2022 - Elsevier
Immunotherapy based on immune checkpoint inhibitors has evolved into a new pillar of
cancer treatment in clinics, but dealing with treatment resistance (either primary or acquired) …

Liver fibrosis assessment: MR and US elastography

A Ozturk, MC Olson, AE Samir, SK Venkatesh - Abdominal Radiology, 2022 - Springer
Elastography has emerged as a preferred non-invasive imaging technique for the clinical
assessment of liver fibrosis. Elastography methods provide liver stiffness measurement …

Randomised clinical trial: semaglutide versus placebo reduced liver steatosis but not liver stiffness in subjects with non‐alcoholic fatty liver disease assessed by …

A Flint, G Andersen, P Hockings… - Alimentary …, 2021 - Wiley Online Library
Background Glucagon‐like peptide‐1 receptor agonists may be a treatment option in
patients with non‐alcoholic fatty liver disease (NAFLD). Aims To investigate the effects of …

[HTML][HTML] Clinical assessment and management of liver fibrosis in non-alcoholic fatty liver disease

A Campos-Murguía, A Ruiz-Margáin… - World journal of …, 2020 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is among the most frequent etiologies of cirrhosis
worldwide, and it is associated with features of metabolic syndrome; the key factor …

US shear-wave elastography dispersion for characterization of chronic liver disease

X Zhang, R Zheng, J Jin, J Wang, T Zhang, J Zeng - Radiology, 2022 - pubs.rsna.org
Background Little is known about the benefits of the use of dispersion slope (DS) as a
viscosity-related parameter derived from two-dimensional (2D) shear-wave elastography …

Multiparametric MRI in patients with nonalcoholic fatty liver disease

JJ Schaapman, ME Tushuizen… - Journal of Magnetic …, 2021 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease in the
world, affecting more than 25% of the adult population. NAFLD covers a spectrum including …

Liver fibrosis imaging: A clinical review of ultrasound and magnetic resonance elastography

YN Zhang, KJ Fowler, A Ozturk, CK Potu… - Journal of Magnetic …, 2020 - Wiley Online Library
Liver fibrosis is a histological hallmark of most chronic liver diseases, which can progress to
cirrhosis and liver failure, and predisposes to hepatocellular carcinoma. Accurate diagnosis …

[HTML][HTML] An individual patient data meta-analysis to determine cut-offs for and confounders of NAFLD-fibrosis staging with magnetic resonance elastography

J Liang, J Ampuero, H Niu, K Imajo, M Noureddin… - Journal of …, 2023 - Elsevier
Background & Aims We conducted an individual patient data meta-analysis to establish
stiffness cut-off values for magnetic resonance elastography (MRE) in staging liver fibrosis …

Mapping heterogenous anisotropic tissue mechanical properties with transverse isotropic nonlinear inversion MR elastography

M McGarry, E Van Houten, D Sowinski, D Jyoti… - Medical image …, 2022 - Elsevier
The white matter tracts of brain tissue consist of highly-aligned, myelinated fibers; white
matter is structurally anisotropic and is expected to exhibit anisotropic mechanical behavior …

Magnetic resonance elastography for prediction of long‐term progression and outcome in chronic liver disease: a retrospective study

T Gidener, M Yin, RA Dierkhising, AM Allen… - …, 2022 - Wiley Online Library
Abstract Background and Aims Although magnetic resonance elastography (MRE) has been
well‐established for detecting and staging liver fibrosis, its prognostic role in determining …