While sleep serves important regulatory functions for mental health, sleep disturbances, in
particular insomnia, may favour a state of allostatic overload impairing brain neuroplasticity …

For hundreds of years, mankind has been influencing its sleep and waking state through the
adenosinergic system. For~ 100 years now, systematic research has been performed, first …

Background Sleep disturbance is common following hospital admission both for COVID-19
and other causes. The clinical associations of this for recovery after hospital admission are …

Orexin is a neurotransmitter produced by a small group of hypothalamic neurons. Besides its
well-known role in the regulation of the sleep-wake cycle, the orexin system was shown to …

Under the burden caused by COVID-19 and rapid lifestyle changes, many people increased
their screen time due to psychological needs and social requirements. The current study …

Abstract In Posttraumatic Stress Disorder (PTSD), fear and anxiety become dysregulated
following psychologically traumatic events. Regulation of fear and anxiety involves both high …

In the modern era, physical and mental stress lead to anxiety at an alarming rate. Therefore,
searching for new lead compounds that deal with anxiety has a practical demand. Our study …

Objective: To explore the functional mechanisms of Suanzaoren decoction (SZRD) for
treating insomnia using network pharmacology and molecular docking. Methods: The active …

Chronic insomnia occurs in~ 10% of the general population and has numerous negative
health effects. The recommended first line treatment of cognitive behavior therapy for …

Background With modernization and ageing in China, the population of older adults living
alone is increasing. Living alone may be a potential risk factor for depressive symptoms …