Proniosomal gel for transdermal delivery of lornoxicam: Optimization using factorial design and in vivo evaluation in rats

H Shah, AB Nair, J Shah, P Bharadia… - DARU Journal of …, 2019 - Springer
Objective Clinical utility of lornoxicam in oral therapy is primarily restricted by the low
solubility and gastric adverse effects. This study evaluated the prospective of optimized …

Formulation by design-based proniosome for accentuated transdermal delivery of risperidone: in vitro characterization and in vivo pharmacokinetic study

SS Imam, M Aqil, M Akhtar, Y Sultana, A Ali - Drug delivery, 2015 - Taylor & Francis
Aim: The aim of this work was to investigate the effects of formulation variables on the
development of risperidone proniosomal formulations as potential transdermal delivery …

Formulation and optimization of nanostructured lipid carriers to enhance oral bioavailability of telmisartan using Box–Behnken design

C Thapa, A Ahad, M Aqil, SS Imam, Y Sultana - Journal of Drug Delivery …, 2018 - Elsevier
The aim of the present study was to formulate and optimize nanostructured lipid carriers
(NLC) to enhance oral bioavailability of telmisartan.“Box-Behnken design (3-factor, 3-level)” …

Enhancement of ocular anti-glaucomic activity of agomelatine through fabrication of hyaluronic acid modified-elastosomes: formulation, statistical optimisation, in vitro …

AA Nemr, GM El-Mahrouk, HA Badie - Journal of …, 2023 - Taylor & Francis
Aim The aim of this manuscript was to fabricate agomelatine (AGM) loaded elastosomes to
improve its corneal permeation and ocular bioavailability. AGM is a biopharmaceutical …

Design and evaluation of proniosomes as a carrier for ocular delivery of lomefloxacin HCl

RM Khalil, GA Abdelbary, M Basha… - Journal of liposome …, 2017 - Taylor & Francis
The current investigation aims to develop and evaluate novel ocular proniosomal gels of
lomefloxacin HCl (LXN); in order to improve its ocular bioavailability for the management of …

Development of novel transdermal self-adhesive films for tenoxicam, an anti-inflammatory drug

DI Nesseem, SF Eid, SS El-Houseny - Life sciences, 2011 - Elsevier
AIM: The purpose of this study was to develop transdermal films (TFs) with the addition of
different polymer ratios that incorporated 0.5% tenoxicam in order to ensure maximum …

Enhanced transdermal delivery of luteolin via non-ionic surfactant-based vesicle: quality evaluation and anti-arthritic assessment

L Abidin, M Mujeeb, SS Imam, M Aqil, D Khurana - Drug delivery, 2016 - Taylor & Francis
Luteolin (LUT) is a promising molecule with potential anti-arthritic activity. This investigation
presents formulation and evaluation of niosomal transgel for enhanced transdermal delivery …

Tenoxicam loaded hyalcubosomes for osteoarthritis

YE Elakkad, MK Younis, RM Allam, AF Mohsen… - International journal of …, 2021 - Elsevier
The main aim is to develop transcutaneous tenoxicam (TNX) loaded vesicles to control
osteoarthritis (OA) without common side effects. Different vesicles were prepared by the …

Development and optimization of boswellic acid-loaded proniosomal gel

M Mehta, H Dureja, M Garg - Drug delivery, 2016 - Taylor & Francis
Abstract Context: Boswellic acids (BAs) are isolated from oleo gum of Boswellia serrata and
are mainly used as potential anti-inflammatory, hypolipidemic, immunomodulatory, and …

Nonionic surfactant-based vesicular system for transdermal drug delivery

S Ghanbarzadeh, A Khorrami, S Arami - Drug delivery, 2015 - Taylor & Francis
Objective: The objective of this study was to formulate and evaluate the Ibuprofen niosomal
formulation as a transdermal drug delivery system. Materials and methods: Niosomes were …