Angiogenic sprouting is a complex, multi-step process involving highly integrated cell
behaviours, initial interaction with the environment and signalling pathways. Endothelial …

Despite the βDTA (Ins2-rtTA; Tet-DTA) mice have been developed as a valuable tool to
study β cell regeneration, their individual variation in therapeutic efficacy has not been …

Diabetes mellitus is a group of metabolic diseases identified through abnormalities in insulin
regulation and glucose metabolism, which can develop into chronic hyperglycaemia, where …

Beschreibungen: Blood vessels are more than just tubes that carry oxygen and nutrients to,
and carbon dioxide and waste products away from tissues. How the vascularization of a …

Diabetes is characterized by insufficient amounts of insulin, a hormone produced by the beta-
cells in the pancreatic islets. While current treatment options such as insulin injections …

The escalating prevalence of obesity and its association with comorbidities like insulin
resistance and type 2 diabetes have raised the interest in adipose tissue biology and its …

The discovery of Vascular endothelial growth factor (VEGF)-B's role in endothelial fatty acid
uptake and tissue lipid accumulation opened a new arena for exploration of VEGF-B in lipid …

Automated Quantification of Human Islet Structure and Geometry Page 1 University of Exeter
College of Engineering Mathematics and Physical Sciences Automated Quantification of Human …

Diabetes mellitus is a disease that has been rapidly increasing in prevalence worldwide,
with more than 9% of the world's adult population currently diagnosed, and an additional 4 …

Cellular crosstalk is essential for proper organogenesis. Although originally assumed to be
simple conduits for blood, endothelial cells (ECs) actively coordinate organ development …