In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

With the increasing morbidity and mortality of invasive fungal infections and the emergence
of severe antifungal drug resistance, new drug targets and novel antifungal agents are …

Constructing a new antibacterial structural framework is an effective strategy to combat drug
resistance. This work discovered a class of naphthalimidopropanediols (NIOLs) as a novel …

Available therapeutic strategies are urgently needed to conquer multidrug resistance of
MRSA. A visible effort was guided towards the advancement of novel antibacterial …

The extensive use of antifungal drugs has resulted in severe drug resistance, making clinical
treatment of fungal infections more difficult. Biofilm inhibitors can overcome drug resistance …

In natural environments, microorganisms form microbial aggregates called biofilms able to
adhere to a multitude of different surfaces. Yeasts make no exception to this rule, being able …

Bacterial, fungal, and parasitic infections increase morbimortality rates and hospital costs.
This study aimed to assess the antimicrobial and antiparasitic activities of the crude extract …

Clinical treatment of candidiasis has suffered from increasingly severe drug resistance and
limited efficacy. Thus, novel strategies to deal with drug resistance are highly desired to …

Control of fungal pathogens is increasingly problematic due to the limited number of
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …

Candidiasis is a highly pervasive infection posing major health risks, especially for
immunocompromised populations. Pathogenic Candida species have evolved intrinsic and …