T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

The role of CXC chemokines in cardiovascular diseases

X Lu, Z Wang, D Ye, Y Feng, M Liu, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease (CVD) is a class of diseases with high disability and mortality rates.
In the elderly population, the incidence of cardiovascular disease is increasing annually …

Whole genome sequence analysis of the plasma proteome in black adults provides novel insights into cardiovascular disease

DH Katz, UA Tahir, AG Bick, A Pampana, D Ngo… - Circulation, 2022 - Am Heart Assoc
Background: Plasma proteins are critical mediators of cardiovascular processes and are the
targets of many drugs. Previous efforts to characterize the genetic architecture of the plasma …

[HTML][HTML] Targeting the chemokine network in atherosclerosis

Y Yan, M Thakur, EPC van der Vorst, C Weber… - Atherosclerosis, 2021 - Elsevier
Chemokines and their receptors represent a potential target for immunotherapy in chronic
inflammation. They comprise a large family of cytokines with chemotactic activity, and their …

Clinical and biological markers for predicting ARDS and outcome in septic patients

J Villar, R Herrán-Monge, E González-Higueras… - Scientific Reports, 2021 - nature.com
Sepsis is a common cause of acute respiratory distress syndrome (ARDS) associated with a
high mortality. A panel of biomarkers (BMs) to identify septic patients at risk for developing …

Molecular drivers of platelet activation: unraveling novel targets for anti-thrombotic and anti-thrombo-inflammatory therapy

M Chatterjee, A Ehrenberg, LM Toska, LM Metz… - International Journal of …, 2020 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of death globally—partly a
consequence of increased population size and ageing—and are major contributors to …

Interleukin-18 accelerates cardiac inflammation and dysfunction during ischemia/reperfusion injury by transcriptional activation of CXCL16

G Zhao, H Zhang, S Zhu, S Wang, K Zhu, Y Zhao, L Xu… - Cellular …, 2021 - Elsevier
Myocardial ischemia/reperfusion (I/R) injury elicits an inflammatory response that drives
tissue damage and cardiac remodeling. The trafficking and recruitment of inflammatory cells …

CXCL16 promotes Ly6Chigh monocyte infiltration and impairs heart function after acute myocardial infarction

J Zhang, W Hao, J Zhang, T Li, Y Ma… - The Journal of …, 2023 - journals.aai.org
High CXCL16 levels during acute cardiovascular events increase long-term mortality.
However, the mechanistic role of CXCL16 in myocardial infarction (MI) is unknown. Here we …

Scavenger receptors in myocardial infarction and ischemia/reperfusion injury: the potential for disease evaluation and therapy

J Zhang, W Ding, J Liu, J Wan… - Journal of the American …, 2023 - Am Heart Assoc
Scavenger receptors (SRs) are a structurally heterogeneous superfamily of evolutionarily
conserved receptors that are divided into classes A to J. SRs can recognize multiple ligands …

Chemokine receptor 5, a double-edged sword in metabolic syndrome and cardiovascular disease

Z Zhang, Q Wang, J Yao, X Zhou, J Zhao… - Frontiers in …, 2020 - frontiersin.org
The key characteristic of cardiovascular disease (CVD) is endothelial dysfunction, which is
likely the consequence of inflammation. It is well demonstrated that chemokines and their …