[HTML][HTML] Sarcoidosis: causes, diagnosis, clinical features, and treatments

R Jain, D Yadav, N Puranik, R Guleria… - Journal of Clinical …, 2020 - mdpi.com
Sarcoidosis is a multisystem granulomatous disease with nonspecific clinical manifestations
that commonly affects the pulmonary system and other organs including the eyes, skin, liver …

[HTML][HTML] The role of diverse immune cells in sarcoidosis

H Zhang, U Costabel, H Dai - Frontiers in immunology, 2021 - frontiersin.org
Sarcoidosis is a systemic inflammatory disorder of unknown etiology characterized by tissue
infiltration with macrophages and lymphocytes and associated non-caseating granuloma …

Comorbidities of sarcoidosis

C Tana, M Drent, H Nunes, V Kouranos… - Annals of …, 2022 - Taylor & Francis
Sarcoidosis is a heterogeneous disease, which can affect virtually every body organ, even
though lungs and intra thoracic lymph nodes are almost universally affected. The presence …

[HTML][HTML] Sarcoidosis as an autoimmune disease

AA Starshinova, AM Malkova, NY Basantsova… - Frontiers in …, 2020 - frontiersin.org
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis
still remain unknown. Most researchers allude to the possible autoimmune or immune …

Clinical and MRI phenotypes of sarcoidosis-associated myelopathy

OC Murphy, A Salazar-Camelo… - Neurology …, 2020 - AAN Enterprises
Objective To determine the characteristic clinical and spinal MRI phenotypes of sarcoidosis-
associated myelopathy (SAM), we analyzed a large cohort of patients with this disorder …

Sarcoidosis and the mTOR, Rac1, and autophagy triad

Y Pacheco, CX Lim, T Weichhart, D Valeyre… - Trends in …, 2020 - cell.com
Sarcoidosis is an enigmatic multisystem disease characterized by the development and
accumulation of granulomas: a compact collection of macrophages that have differentiated …

Genetic predisposition to sarcoidosis

SY Liao, T Fingerlin, L Maier - Journal of Autoimmunity, 2023 - Elsevier
Sarcoidosis is a complex systemic disease with clinical heterogeneity based on varying
phenotypes and natural history. The detailed etiology of sarcoidosis remains unknown, but …

Proinflammatory histidyl–transfer RNA synthetase–specific CD 4+ T cells in the blood and lungs of patients with idiopathic inflammatory myopathies

AS Galindo‐Feria, I Albrecht… - Arthritis & …, 2020 - Wiley Online Library
Objective Autoantibodies targeting histidyl–transfer RNA synthetase (His RS; anti–Jo‐1) are
common in the idiopathic inflammatory myopathies (IIM s) and antisynthetase syndrome …

New concepts in the pathogenesis of sarcoidosis

D Bennett, E Bargagli, RM Refini… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The pathogenesis of sarcoidosis is not yet completely understood, although in
recent years our knowledge has made considerable progress. Areas covered: This review …

[HTML][HTML] FOXP3+ regulatory T cells are associated with the severity and prognosis of sarcoidosis

KC Patterson, WT Miller, WW Hancock… - Frontiers in …, 2023 - frontiersin.org
Rationale Sarcoidosis is an inflammatory granulomatous disease of unknown etiology with
predominant lung involvement. Organ involvement and disease severity, as well as the …