Context: Osteoporosis primarily affects postmenopausal women. However, young women
with estrogen deficiency also are at increased risk for low bone density. Objective: The aim …

The concept of covariate adjustment is well established in therapeutic and etiologic studies.
However, it has received little attention in the growing area of medical research devoted to …

Classification accuracy is the ability of a marker or diagnostic test to discriminate between
two groups of individuals, cases and controls, and is commonly summarized by using the …

In case–control studies evaluating the classification accuracy of a marker, controls are often
matched to cases with respect to factors associated with the marker and disease status. In …

The predictiveness curve shows the population distribution of risk endowed by a marker or
risk prediction model. It provides a means for assessing the model's capacity for stratifying …

The classification accuracy of a continuous marker is typically evaluated with the receiver
operating characteristic (ROC) curve. In this paper, we study an alternative conceptual …

Background The usefulness of in-phase/opposed-phase imaging and diffusion weighted
imaging (DWI) in differentiating benign and neoplastic vertebral fractures has been …

Classification accuracy is the ability of a marker or diagnostic test to discriminate between
two groups of individuals, cases and controls, and is commonly summarized using the …

The past decade has seen an explosion in the availability and use of biomarkers data as a
result of innovative discoveries and recent development of new biological and molecular …

The past decade has seen an explosion in the availability and use of biomarker data as a
result of innovative discoveries and recent development of new biological and molecular …