[HTML][HTML] Molecular mechanisms of high-altitude acclimatization

RT Mallet, J Burtscher, V Pialoux, Q Pasha… - International journal of …, 2023 - mdpi.com
High-altitude illnesses (HAIs) result from acute exposure to high altitude/hypoxia. Numerous
molecular mechanisms affect appropriate acclimatization to hypobaric and/or normobaric …

[HTML][HTML] The brain at high altitude: from molecular signaling to cognitive performance

MA Aboouf, M Thiersch, J Soliz, M Gassmann… - International Journal of …, 2023 - mdpi.com
The brain requires over one-fifth of the total body oxygen demand for normal functioning. At
high altitude (HA), the lower atmospheric oxygen pressure inevitably challenges the brain …

[HTML][HTML] Establishing a prediction model of severe acute mountain sickness using machine learning of support vector machine recursive feature elimination

M Yang, Y Wu, X Yang, T Liu, Y Zhang, Y Zhuo… - Scientific Reports, 2023 - nature.com
Severe acute mountain sickness (sAMS) can be life-threatening, but little is known about its
genetic basis. The study was aimed to explore the genetic susceptibility of sAMS for the …

[HTML][HTML] Potential plasma biomarkers at low altitude for prediction of acute mountain sickness

H Guo, Q Wang, T Li, J Chen, C Zhang, Y Xu… - Frontiers in …, 2023 - frontiersin.org
Background Ascending to high altitude can induce a range of physiological and molecular
alterations, rendering a proportion of lowlanders unacclimatized. The prediction of acute …

[HTML][HTML] Serum vascular endothelial growth factor is a potential biomarker for acute mountain sickness

N Nourkami-Tutdibi, J Küllmer, S Dietrich… - Frontiers in …, 2023 - frontiersin.org
Background: Acute mountain sickness (AMS) is the most common disease caused by
hypobaric hypoxia (HH) in high-altitude (HA) associated with high mortality when …

[HTML][HTML] Urinary proteomics for noninvasive monitoring of biomarkers of chronic mountain sickness in a young adult population using data-independent acquisition …

K Fan, J Wang, W Zhu, X Zhang, F Deng, Y Zhang… - Journal of …, 2024 - Elsevier
Different populations exhibit varying pathophysiological responses to plateau environments.
Therefore, it is crucial to identify molecular markers in body fluids with high specificity and …

[PDF][PDF] Predicting Acute Mountain Sickness by Using Sea-level Regional Cerebral Blood Flow

H ZHANG, J FENG, SY ZHANG, WJ LIU, L MA - 2024 - besjournal.com
Objective We aim to investigate the role of sea-level cerebral blood flow (CBF) in the
prediction of acute mountain sickness (AMS) by using three-dimensional pseudo-continuous …

Establishing a prediction model of severe acute mountain sickness using deep learning of support vector machine recursive feature elimination

M Yang, Y Wu, X Yang, J Tao, T Liu, W Li, J Yan… - 2023 - researchsquare.com
Background Severe acute mountain sickness (sAMS) can be life-threatening, but little is
known about its genetic basis. Using microarray genotype data and phenotype data for deep …