Recent developments and future perspectives of microfluidics and smart technologies in wearable devices

S Apoorva, NT Nguyen, SK Rajan - Lab on a Chip, 2024 - pubs.rsc.org
Wearable devices are gaining popularity in the fields of health monitoring, diagnosis, and
drug delivery. Recent advances in wearable technology have enabled real-time analysis of …

Novel microneedle platforms for the treatment of wounds by drug delivery: a review

H An, Z Gu, Z Huang, T Huo, Y Xu, Y Dong… - Colloids and Surfaces B …, 2023 - Elsevier
The management and treatment of wounds are complex and pose a substantial financial
burden to the patient. However, the complex environment of wounds leads to inadequate …

A Bacterial Responsive Microneedle Dressing with Hydrogel Backing Layer for Chronic Wound Treatment

L Yang, Y Gao, Q Liu, W Li, Z Li, D Zhang, R Xie… - Small, 2024 - Wiley Online Library
The treatment of chronic wounds still presents great challenges due to being infected by
biofilms and the damaged healing process. The current treatments do not address the needs …

Targeting Diverse Wounds and Scars: Recent Innovative Bio‐design of Microneedle Patch for Comprehensive Management

ZM Zhuang, Y Wang, ZX Feng, XY Lin, ZC Wang… - Small, 2024 - Wiley Online Library
Wounds and the subsequent formation of scars constitute a unified and complex phased
process. Effective treatment is crucial; however, the diverse therapeutic approaches for …

Reactive Oxygen Species Responsive Nitric Oxide Release for Enhanced Photodynamic Antibacterial Therapy of Scaffolds

F Qi, W Liu, Z Li, S Peng, Y Chen, W Tan… - ACS Applied Polymer …, 2024 - ACS Publications
Photodynamic therapy (PDT) presented tremendous potential for combating implant-related
infections, but its antibacterial efficacy was constrained by rapid electron–hole pair …

A universal powder-laden crosslinked chitosan microneedle patch for high-dose controllable drug delivery

Y He, M Zang, J Zhang, H Cheng, Y Cui… - International Journal of …, 2024 - Elsevier
In this study, we constructed a novel powder-laden core–shell crosslinked chitosan
microneedle patch for high-dose and controllable delivery of various drugs, including both …

Enhanced Antimicrobial Screening Sensitivity Enabled the Identification of an Ultrashort Peptide KR-8 for Engineering of LL-37mini to Combat Drug-Resistant …

AF Mechesso, Y Su, J Xie, G Wang - ACS Infectious Diseases, 2023 - ACS Publications
Identification of novel antibiotics is of top importance because of the threat of antibiotic-
resistant pathogens. Antimicrobial screening in Mueller-Hinton broth is frequently the first …

It Takes Two to Tangle: Microneedle Patches Co‐delivering Monoclonal Antibodies and Engineered Antimicrobial Peptides Effectively Eradicate Wound Biofilms

Y Su, SSM Shahriar, SM Andrabi… - Macromolecular …, 2024 - Wiley Online Library
Wound biofilms pose a great clinical challenge. Herein, this work reports a dissolvable
microneedle patch for dual delivery of monoclonal antibodies anti‐PBP2a and engineers …

Morphology design of polymer microneedle arrays: key factors from the application perspective

B Jia, T Xia, X Wang, Y Xu, Z Guo - Journal of Drug Delivery Science and …, 2023 - Elsevier
Microneedles invade skin tissue in a minimally invasive manner, with a small traumatic
surface and slight pain. There is growing interest in the potential application of microneedle …

Application of hydrogel microneedles in the oral cavity

Y He, D He, L Fan, S Ren, L Wang, J Sun - Biopolymers, 2024 - Wiley Online Library
Microneedles are a transdermal drug delivery system in which the needle punctures the
epithelium to deliver the drug directly to deep tissues, thus avoiding the influence of the first …