[HTML][HTML] Generation of three-dimensional meat-like tissue from stable pig epiblast stem cells
G Zhu, D Gao, L Li, Y Yao, Y Wang, M Zhi… - Nature …, 2023 - nature.com
Cultured meat production has emerged as a breakthrough technology for the global food
industry with the potential to reduce challenges associated with environmental sustainability …
industry with the potential to reduce challenges associated with environmental sustainability …
[HTML][HTML] Single-cell transcriptomic characterization of sheep conceptus elongation and implantation
GX Jia, WJ Ma, ZB Wu, S Li, XQ Zhang, Z He, SX Wu… - Cell Reports, 2023 - cell.com
Bidirectional communication between the developing conceptus and endometrium is
essential for pregnancy recognition and establishment in ruminants. We dissect the …
essential for pregnancy recognition and establishment in ruminants. We dissect the …
Research progress and application prospects of stable porcine pluripotent stem cells
J Zhang, M Zhi, D Gao, Q Zhu, J Gao… - Biology of …, 2022 - academic.oup.com
Pluripotent stem cells (PSCs) harbor the capacity of unlimited self-renewal and multilineage
differentiation potential, which are crucial for basic research and biomedical science …
differentiation potential, which are crucial for basic research and biomedical science …
An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells
Pigs share anatomical and physiological traits with humans and can serve as a large-animal
model for translational medicine. Bona fide porcine pluripotent stem cells (PSCs) could …
model for translational medicine. Bona fide porcine pluripotent stem cells (PSCs) could …
Super-enhancers conserved within placental mammals maintain stem cell pluripotency
J Zhang, Y Zhou, W Yue, Z Zhu, X Wu… - Proceedings of the …, 2022 - National Acad Sciences
Despite pluripotent stem cells sharing key transcription factors, their maintenance involves
distinct genetic inputs. Emerging evidence suggests that super-enhancers (SEs) can …
distinct genetic inputs. Emerging evidence suggests that super-enhancers (SEs) can …
[HTML][HTML] Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing
JV Conrad, S Meyer, PS Ramesh, JA Neira… - Stem Cell Reports, 2023 - cell.com
Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical
studies because of its comparable physiology and organ size to humans. The derivation of …
studies because of its comparable physiology and organ size to humans. The derivation of …
[HTML][HTML] Pig blastocyst-like structure models from embryonic stem cells
J Xiang, H Wang, B Shi, J Li, D Liu, K Wang, Z Wang… - Cell Discovery, 2024 - nature.com
Pluripotent stem cells have the potential to generate embryo models that can recapitulate
developmental processes in vitro. Large animals such as pigs may also benefit from stem …
developmental processes in vitro. Large animals such as pigs may also benefit from stem …
[HTML][HTML] Spatio-temporal transcriptome dynamics coordinate rapid transition of core crop functions in 'lactating'pigeon
Y Wang, X Wang, Y Luo, J Zhang, Y Lin, J Wu… - PLoS …, 2023 - journals.plos.org
Pigeons (Columba livia) are among a select few avian species that have developed a
specialized reproductive mode wherein the parents produce a 'milk'in their crop to feed …
specialized reproductive mode wherein the parents produce a 'milk'in their crop to feed …
Generation of stable integration‐free pig induced pluripotent stem cells under chemically defined culture condition
Q Zhu, F Wang, D Gao, J Gao, G Li, D Jiao… - Cell …, 2023 - Wiley Online Library
Genome integration‐free pig induced pluripotent stem cells (iPSCs) bring tremendous value
in pre‐clinical testing of regenerative medicine, as well as conservation and exploitation of …
in pre‐clinical testing of regenerative medicine, as well as conservation and exploitation of …
[HTML][HTML] Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signaling
VB Alarcon, Y Marikawa - Reproduction, 2022 - rep.bioscientifica.com
In brief Trophectoderm is the first tissue to differentiate in the early mammalian embryo and
is essential for hatching, implantation, and placentation. This review article discusses the …
is essential for hatching, implantation, and placentation. This review article discusses the …