Cerebrovascular disease is the most common life-threatening and debilitating condition that
often leads to stroke. The multifunctional calcium/calmodulin-dependent protein kinase II …

Glutamatergic synapses harbor abundant amounts of the multifunctional Ca2+/calmodulin
dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the …

Abstract 'Dominant mutations in CAMK2B, encoding a subunit of the calcium/calmodulin-
dependent protein kinase II (CAMK2), a serine/threonine kinase playing a key role in …

Neurodevelopmental disorders are a complex and heterogeneous group of neurological
disorders characterized by their early-onset and estimated to affect more than 3% of children …

Calcium/calmodulin-dependent protein kinase II (CaMKII) plays a central role in Ca2+
signaling throughout the body. In the hippocampus, CaMKII is required for learning and …

Neurotransmitter-initiated signaling pathway were reported to play an important role in
regulating the malignant phenotype of tumor cells. Cancer cells could exhibit a “neural …

Summary Ca 2+/calmodulin-dependent protein kinase II (CaMKII) is a signaling protein
required for long-term memory. When activated by Ca 2+/CaM, it sustains activity even after …

The calcium/calmodulin-dependent protein kinase type 2 (CAMK2) family consists of four
different isozymes, encoded by four different genes—CAMK2A, CAMK2B, CAMK2G, and …

Understanding how protein function has evolved and diversified is of great importance for
human genetics and medicine. Here, we tackle the problem of describing the whole …

Myotonic dystrophy type 1 (DM1) is a severe neuromuscular disease mediated by a toxic
gain of function of mutant RNAs. The neuropsychological manifestations affect multiple …