Potential of copper and copper compounds for anticancer applications

P Ji, P Wang, H Chen, Y Xu, J Ge, Z Tian, Z Yan - Pharmaceuticals, 2023 - mdpi.com
Inducing cancer cell death has always been a research hotspot in life sciences. With the
continuous deepening and diversification of related research, the potential value of metal …

The 4-hydroxynonenal–protein adducts and their biological relevance: are some proteins preferred targets?

L Milkovic, N Zarkovic, Z Marusic, K Zarkovic… - Antioxidants, 2023 - mdpi.com
It is well known that oxidative stress and lipid peroxidation (LPO) play a role in physiology
and pathology. The most studied LPO product with pleiotropic capabilities is 4 …

Functions of astrocytes under normal conditions and after a brain disease

SL Valles, SK Singh, J Campos-Campos… - International Journal of …, 2023 - mdpi.com
In the central nervous system (CNS) there are a greater number of glial cells than neurons
(between five and ten times more). Furthermore, they have a greater number of functions …

[HTML][HTML] Oxidative stress, the blood–brain barrier and neurodegenerative diseases: The critical beneficial role of dietary antioxidants

J Feng, Y Zheng, M Guo, I Ares, M Martínez… - … Pharmaceutica Sinica B, 2023 - Elsevier
In recent years, growing awareness of the role of oxidative stress in brain health has
prompted antioxidants, especially dietary antioxidants, to receive growing attention as …

[HTML][HTML] Stimulator of interferon genes (STING): key therapeutic targets in ischemia/reperfusion injury

J Lv, X Zhu, C Xing, Y Chen, H Bian, H Yin, X Gu… - Biomedicine & …, 2023 - Elsevier
Abstract The Stimulator of Interferon Genes (STING) is predominantly expressed in immune
cells, including macrophages, natural killer cells, dendritic cells, and T cells, functioning as a …

Antioxidant and anti-photoaging effects of a fucoidan isolated from Turbinaria ornata

L Wang, TU Jayawardena, J Hyun, K Wang… - International Journal of …, 2023 - Elsevier
Fucoidans isolated from brown seaweeds are potential ingredients in the cosmetic industry.
In our preosvious study, a fucoidan was isolated from the brown seaweed Turbinaria ornata …

The interconnection between hepatic insulin resistance and metabolic dysfunction-associated steatotic liver disease—the transition from an adipocentric to liver …

M Vesković, N Šutulović, D Hrnčić… - Current issues in …, 2023 - mdpi.com
The central mechanism involved in the pathogenesis of MAFLD is insulin resistance with
hyperinsulinemia, which stimulates triglyceride synthesis and accumulation in the liver. On …

The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

[HTML][HTML] Innovative therapeutic strategies for cardiovascular disease

K Maiese - EXCLI journal, 2023 - ncbi.nlm.nih.gov
As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …

The effect of different doses of nonylphenol on the blood-testicular barrier integrity, hormone level, and DNA damage in the testes of rats

O Goktepe, GO Onder, E Cetindag, N Bitgen… - Food and Chemical …, 2023 - Elsevier
Determining the molecular characteristics of the damage caused by NP exposure in the
testis is very important for understanding the source of the damage and developing …