Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …

Diabetes mellitus (DM) is among the biggest global health problems of the 21st century,
which is characterised by insufficient insulin secretion and results in the augmentation of …

Posttranslational modifications (PTMs), such as phosphorylation, methylation, ubiquitination,
and acetylation, are important in governing protein expression levels. Proteolysis targeting …

Abstract Scutebarbatine A (SBT-A), a diterpenoid alkaloid, has exerted cytotoxicity on
hepatocellular carcinoma cells in our previous works. Here, the antitumor activity of SBT-A in …

Background: EGFR has been considered a vital molecular target in cancer management.
Aim: The discovery of new thieno [2, 3-d] pyrimidine derivatives as EGFR tyrosine kinase …

This study aims to develop sunitinib niosomal formulations and assess their in-vitro anti-
cancer efficiency against lung cancer cell line, A549. Sunitinib, a highly effective anticancer …

Cancer is a progressive disease that is caused by a combination of factors, including one's
genetics, environment, and lifestyle choices. The pillars of cancer management include …

Cancer development in various organs, including the breast, ovary, brain, bladder, colon,
and lung, is frequently connected to disturbances in the epidermal growth factor receptor …

In the spectrum of breast neoplasms, approximately 15 to 20% of all diagnosed cases are
triple-negative breast carcinoma. TNBC grows and spreads faster than other invasive breast …

Background/Introduction As the most common form of pre-invasive breast cancer, ductal
carcinoma in situ (DCIS) affects over 50,000 women in the US annually. Despite …