Obesity/overweight are important health problems due to metabolic complications.
Dysregulation of peptides exerting orexigenic/anorexigenic effects must be investigated in …

Pain and obesity, as well as their associated impairments, are major health concerns.
Understanding the relationship between the two is the focus of a growing body of research …

Abstract Knowledge gaps that limit the development of therapies for polycystic ovary
syndrome (PCOS) concern various environmental factors that impact clinical characteristics …

Opioid receptors belong to the class AG‐protein‐coupled receptors and are activated by
alkaloid opiates such as morphine, and endogenous ligands such as endorphins and …

Background Type 2 diabetes mellitus is a complex metabolic disorder associated with
obesity, glucose intolerance and insulin resistance. Activation of GALR2 has been proposed …

Orexins are excitatory neuropeptides, which are predominantly associated with feeding
behavior, sleep-wake cycle and energy homeostasis. The orexinergic system comprises of …

Simple Summary Peptidergic systems play an important role in cancer progression. The
galaninergic system (the peptide galanin and its receptors: galanin 1, 2 and 3) is involved in …

The neuropeptide galanin receptor 3 (GALR3) is a class AG protein-coupled receptor
(GPCR) broadly expressed in the nervous system, including the retina. GALR3 is involved in …

Age is a major risk factor for developing metabolic diseases such as obesity and diabetes.
There is an unprecedented rise in obesity and type 2 diabetes in recent decades. A …

Spexin (SPX) is a novel adipokine that plays an emerging role in metabolic diseases due to
its involvement in carbohydrate homeostasis, weight loss, appetite control, and …