Hydroxyapatite (HA) reinforced collagen fibrils serve as the basic building blocks of natural
bone and dentin. Mineralization of collagen fibrils play an essential role in ensuring the …

The mineralization of type I collagen is a biological process occurring in vertebrates by
which some hard tissues such as bone and dentin are constructed. Due to the extensive …

Non-collagenous proteins (NCPs) in the extracellular matrix (ECM) of bone and dentin are
known to play a critical regulatory role in the induction of collagen fibril mineralization and …

Osteoporosis leads to various complications, such as prosthesis loosening and
periprosthetic fracture, after joint replacement. This is mainly due to the impaired …

Biomolecules play a vital role in the regulation of biomineralization. However, the
characteristics of practical nucleation domains are still sketchy. Herein, the effects of the …

Interfacial failure at the resin-dentin interface is a significant disadvantage of resin-based
dental restoration. In this study, we created bio-inspired bio-nano complexes using the …

Osteocalcin is the most prevalent, noncollagenous protein found in the bone [1, 2]. It is
synthesized by osteoblasts and contains 3 glutamic acid residues which are post …

Bone biomineralization is a complex process in which type I collagen and associated non-
collagenous proteins (NCPs), including glycoproteins and proteoglycans, interact closely …

The treatment of bone tissue defects remains a complicated clinical challenge. Recently, the
bone tissue engineering (BTE) technology has become an important therapeutic approach …

Abstract According to the World Health Organization, dental caries is the most prevalent
chronic disease worldwide. Remineralization of demineralized dentin, especially within the …