CRISPR-Cas9 system: A new-fangled dawn in gene editing

D Gupta, O Bhattacharjee, D Mandal, MK Sen, D Dey… - Life sciences, 2019 - Elsevier
Till date, only three techniques namely Zinc Finger Nuclease (ZFN), Transcription-Activator
Like Effector Nucleases (TALEN) and Clustered Regularly Interspaced Short Palindromic …

A review of the global burden, new diagnostics, and current therapeutics for amebiasis

DAT Shirley, L Farr, K Watanabe… - Open forum infectious …, 2018 - academic.oup.com
Amebiasis, due to the pathogenic parasite Entamoeba histolytica, is a leading cause of
diarrhea globally. Largely an infection of impoverished communities in developing countries …

Malnutrition and gut microbiota in children

I Iddrisu, A Monteagudo-Mera, C Poveda, S Pyle… - Nutrients, 2021 - mdpi.com
Malnutrition continues to threaten the lives of millions across the world, with children being
hardest hit. Although inadequate access to food and infectious disease are the primary …

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

W Checkley, AC White, D Jaganath… - The Lancet Infectious …, 2015 - thelancet.com
Cryptosporidium spp are well recognised as causes of diarrhoeal disease during
waterborne epidemics and in immunocompromised hosts. Studies have also drawn …

Persistent gut microbiota immaturity in malnourished Bangladeshi children

S Subramanian, S Huq, T Yatsunenko, R Haque… - Nature, 2014 - nature.com
Therapeutic food interventions have reduced mortality in children with severe acute
malnutrition (SAM), but incomplete restoration of healthy growth remains a major problem …

Impact of childhood malnutrition on host defense and infection

MK Ibrahim, M Zambruni, CL Melby… - Clinical microbiology …, 2017 - Am Soc Microbiol
The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

Cryptosporidium and Giardia in Africa: current and future challenges

SA Squire, U Ryan - Parasites & vectors, 2017 - Springer
Cryptosporidium and Giardia are important causes of diarrhoeal illness. Adequate
knowledge of the molecular diversity and geographical distribution of these parasites and …

Practical guidance for clinical microbiology laboratories: laboratory diagnosis of parasites from the gastrointestinal tract

LS Garcia, M Arrowood, E Kokoskin… - Clinical microbiology …, 2018 - Am Soc Microbiol
SUMMARY This Practical Guidance for Clinical Microbiology document on the laboratory
diagnosis of parasites from the gastrointestinal tract provides practical information for the …

Environmental enteric dysfunction and child stunting

S Budge, AH Parker, PT Hutchings, C Garbutt - Nutrition reviews, 2019 - academic.oup.com
In 2017, an estimated 1 in every 4 (23%) children aged< 5 years were stunted worldwide.
With slow progress in stunting reduction in many regions and the realization that a large …

Cryptosporidium in humans and animals—a one health approach to prophylaxis

U Ryan, A Zahedi, A Paparini - Parasite immunology, 2016 - Wiley Online Library
Cryptosporidium is a major cause of moderate‐to‐severe diarrhoea in humans worldwide,
second only to rotavirus. Due to the wide host range and environmental persistence of this …