Assessing the state of chronic spinal cord injury using diffusion tensor imaging

E Koskinen, A Brander, U Hakulinen, T Luoto… - Journal of …, 2013 - liebertpub.com
The aim of this study was to quantify the association between diffusion tensor imaging (DTI)
parameters of the cervical spinal cord and neurological disability in patients with chronic …

[HTML][HTML] Alterations in cortical sensorimotor connectivity following complete cervical spinal cord injury: a prospective resting-state fMRI study

A Oni-Orisan, M Kaushal, W Li, J Leschke, BD Ward… - PLoS …, 2016 - journals.plos.org
Functional magnetic resonance imaging (fMRI) studies have demonstrated alterations
during task-induced brain activation in spinal cord injury (SCI) patients. The interruption to …

[HTML][HTML] Promoting the Differentiation of Neural Progenitor Cells into Oligodendrocytes through the Induction of Olig2 Expression: A Transcriptomic Study Using RNA …

K Pieczonka, M Khazaei, MG Fehlings - Cells, 2023 - mdpi.com
Oligodendrocytes are the myelinating cells of the central nervous system that facilitate
efficient signal transduction. The loss of these cells and the associated myelin sheath can …

Diffusion tensor imaging as a predictor of locomotor function after experimental spinal cord injury and recovery

BJ Kelley, NY Harel, CY Kim, X Papademetris… - Journal of …, 2014 - liebertpub.com
Traumatic spinal cord injury (SCI) causes long-term disability with limited functional recovery
linked to the extent of axonal connectivity. Quantitative diffusion tensor imaging (DTI) of …

[HTML][HTML] Degeneration of the injured cervical cord is associated with remote changes in corticospinal tract integrity and upper limb impairment

P Freund, T Schneider, Z Nagy, C Hutton, N Weiskopf… - PloS one, 2012 - journals.plos.org
Background Traumatic spinal cord injury (SCI) leads to disruption of axons and macroscopic
tissue loss. Using diffusion tensor imaging (DTI), we assessed degeneration of the …

Extent of cord pathology in the lumbosacral enlargement in non-traumatic versus traumatic spinal cord injury

G David, K Vallotton, M Hupp, A Curt… - Journal of …, 2022 - liebertpub.com
This study compares remote neurodegenerative changes caudal to a cervical injury in
degenerative cervical myelopathy (DCM; ie, non-traumatic) and incomplete traumatic spinal …

Spinal cord injury: how can we improve the classification and quantification of its severity and prognosis?

V Krishna, H Andrews, A Varma, J Mintzer… - Journal of …, 2014 - liebertpub.com
The preservation of functional neural tissue after spinal cord injury (SCI) is the basis for
spontaneous neurological recovery. Some injured patients in the acute phase have more …

Longitudinal assessment of white matter pathology in the injured mouse spinal cord through ultra-high field (16.4 T) in vivo diffusion tensor imaging

FH Brennan, GJ Cowin, ND Kurniawan, MJ Ruitenberg - Neuroimage, 2013 - Elsevier
This study examined the sensitivity of ultra-high field (16.4 T) diffusion tensor imaging (DTI;
70 μm in-plane resolution, 1 mm slice thickness) to evaluate the spatiotemporal …

Diffusion MRI of the spinal cord: from structural studies to pathology

Y Cohen, D Anaby, D Morozov - NMR in Biomedicine, 2017 - Wiley Online Library
Diffusion MRI is extensively used to study brain microarchitecture and pathologies, and
water diffusion appears highly anisotropic in the white matter (WM) of the spinal cord (SC) …

Electrophysiological multimodal assessments improve outcome prediction in traumatic cervical spinal cord injury

M Hupp, C Pavese, LM Bachmann, R Koller… - Journal of …, 2018 - liebertpub.com
Outcome prediction after spinal cord injury (SCI) is essential for early counseling and
orientation of the rehabilitative intervention. Moreover, prognostication of outcome is crucial …