With progress in genome-wide association studies of depression, from identifying zero hits
in~ 16 000 individuals in 2013 to 223 hits in more than a million individuals in 2020 …

Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …

For many years, psychiatrists have tried to understand factors involved in response to
medications or psychotherapies, in order to personalize their treatment choices. There is …

This chapter addresses fundamental issues of change in psychotherapy: how to measure,
monitor, predict change, and provide feedback on treatment outcome. The chapter starts …

Pharmacometrics is a multidisciplinary field utilizing mathematical models of physiology,
pharmacology, and disease to describe and quantify the interactions between medication …

Empirical evidence is mounting that monitoring momentary experiences for the presence of
early warning signals (EWS) may allow for personalized predictions of meaningful symptom …

Improving response and remission rates in major depressive disorder (MDD) remains an
important challenge. Matching patients to the treatment they will most likely respond to …

Background: Psychiatric disorders have been historically classified using symptom
information alone. Recently, there has been a dramatic increase in research interest not only …

Abstract Background/Objective Screening for depression in patients with cancer can be
difficult due to overlap between symptoms of depression and cancer. We assessed validity …

Predicting treatment outcome in major depressive disorder (MDD) remains an essential
challenge for precision psychiatry. Clinical prediction models (CPMs) based on supervised …