Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications

Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

Translational aspect in peptide drug discovery and development: An emerging therapeutic candidate

U Anand, A Bandyopadhyay, NK Jha… - Biofactors, 2023 - Wiley Online Library
In the last two decades, protein–protein interactions (PPIs) have been used as the main
target for drug development. However, with larger or superficial binding sites, it has been …

Structure-activity relationship for antibacterial chitosan carrying cationic and hydrophobic moieties

P Sahariah, GI Kontogianni, E Scoulica… - Carbohydrate …, 2023 - Elsevier
To overcome the problem of antibiotic resistance and toxicity of synthetic polymers, herein
we report the synthesis of biocompatible polymers which can serve as broad spectrum …

Biomimetic antimicrobial polymers—Design, characterization, antimicrobial, and novel applications

H Takahashi, I Sovadinova, K Yasuhara… - Wiley …, 2023 - Wiley Online Library
Biomimetic antimicrobial polymers have been an area of great interest as the need for novel
antimicrobial compounds grows due to the development of resistance. These polymers were …

Design and applications of polymer-like peptides in biomedical nanogels

I Neamtu, A Ghilan, AG Rusu, LE Nita… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Polymer nanogels are among the most promising nanoplatforms for use in
biomedical applications. The substantial interest for these drug carriers is to enhance the …

Combining SNAPs with antibiotics shows enhanced synergistic efficacy against S. aureus and P. aeruginosa biofilms

RG Maset, A Hapeshi, J Lapage, N Harrington… - npj Biofilms and …, 2023 - nature.com
Biofilm infections are associated with a high mortality risk for patients. Antibiotics perform
poorly against biofilm communities, so high doses and prolonged treatments are often used …

Advances in nonfouling and antimicrobial coatings: Perspectives for the food industry

AM Rudlong, YT Koga, JM Goddard - ACS Food Science & …, 2022 - ACS Publications
Microbial cross-contamination represents a significant burden to public health and food
wasted due to microbial spoilage. Despite established protocols for cleaning and sanitizing …

[HTML][HTML] Surface modification of polyester films with polyfunctional amines: Effect on bacterial biofilm formation

G Mallamaci, B Brugnoli, A Mariano, AS d'Abusco… - Surfaces and …, 2023 - Elsevier
The development of materials with antifouling properties is crucial in many areas, including
medicine and food packaging. In this study, 2D-matrices made of polylactic acid (PLA) …

Mechanism of Action of Oxazoline‐Based Antimicrobial Polymers Against Staphylococcus aureus: In Vivo Antimicrobial Activity Evaluation

M Concilio, R Garcia Maset… - Advanced …, 2023 - Wiley Online Library
Antimicrobial‐resistant pathogens have reached alarming levels, becoming one of the most
pressing global health issues. Hence, new treatments are necessary for the fight against …

Bioselectivity of silk protein-based materials and their bio-inspired applications

H Bargel, VT Trossmann, C Sommer… - Beilstein Journal of …, 2022 - beilstein-journals.org
Adhesion to material surfaces is crucial for almost all organisms regarding subsequent
biological responses. Mammalian cell attachment to a surrounding biological matrix is …