[HTML][HTML] Astrocyte-neuron circuits in epilepsy

BS Purnell, M Alves, D Boison - Neurobiology of disease, 2023 - Elsevier
The epilepsies are a diverse spectrum of disease states characterized by spontaneous
seizures and associated comorbidities. Neuron-focused perspectives have yielded an array …

[HTML][HTML] Cerebral microcirculation, perivascular unit, and glymphatic system: role of aquaporin-4 as the gatekeeper for water homeostasis

J Szczygielski, M Kopańska, A Wysocka… - Frontiers in …, 2021 - frontiersin.org
In the past, water homeostasis of the brain was understood as a certain quantitative
equilibrium of water content between intravascular, interstitial, and intracellular spaces …

[HTML][HTML] The Role of Aquaporins in Epileptogenesis—A Systematic Review

L Bonosi, UE Benigno, S Musso, K Giardina… - International Journal of …, 2023 - mdpi.com
Aquaporins (AQPs) are a family of membrane proteins involved in the transport of water and
ions across cell membranes. AQPs have been shown to be implicated in various …

[HTML][HTML] Voluntary running wheel exercise induces cognitive improvement post traumatic brain injury in mouse model through redressing aberrant excitation regulated …

D Wang, HX Zhang, GJ Yan, HR Zhao… - Experimental Brain …, 2024 - Springer
Traumatic brain injury (TBI) leads to disturbed brain discharge rhythm, elevated excitability,
anxiety-like behaviors, and decreased learning and memory capabilities. Cognitive …

[HTML][HTML] From physiology to pathology of cortico-thalamo-cortical oscillations: astroglia as a target for further research

D Gobbo, A Scheller, F Kirchhoff - Frontiers in Neurology, 2021 - frontiersin.org
The electrographic hallmark of childhood absence epilepsy (CAE) and other idiopathic
forms of epilepsy are 2.5–4 Hz spike and wave discharges (SWDs) originating from …

Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders

Z Yaghoobi, SS Seyed Bagher Nazeri, A Asadi… - Neurochemical …, 2024 - Springer
Neurological disorders are a major group of non-communicable diseases affecting quality of
life. Non-Coding RNAs (ncRNAs) have an important role in the etiology of neurological …

[HTML][HTML] The neurovascular unit dysfunction in the molecular mechanisms of epileptogenesis and targeted therapy

X Liu, Y Zhang, Y Zhao, Q Zhang, F Han - Neuroscience Bulletin, 2024 - Springer
Epilepsy is a multifaceted neurological syndrome characterized by recurrent, spontaneous,
and synchronous seizures. The pathogenesis of epilepsy, known as epileptogenesis …

Glymphatic system and aquaporin‑4 in epilepsy

D Nowicka - Acta Neurobiologiae Experimentalis, 2023 - ane.pl
Over the past decade glymphatic concept has gained more and more interest. Despite some
lacking data regarding structural and functional aspects, glymphatic system is widely …

[HTML][HTML] Transcriptome sequencing of ceRNA network constructing in status epilepticus mice treated by low-frequency repetitive transcranial magnetic stimulation

S Zhang, H Zou, X Zou, J Ke, B Zheng, X Chen… - Journal of Molecular …, 2023 - Springer
It is shown that great progress was recently made in the treatment of repetitive transcranial
magnetic stimulation (rTMS) for neurological and psychiatric diseases. This study aimed to …

Acutely increased aquaporin-4 exhibits more potent protective effects in the cortex against single and repeated isoflurane-induced neurotoxicity in the developing rat …

H Yılmaz, A Şengelen, S Demirgan… - Toxicology …, 2023 - Taylor & Francis
Damage to hippocampus, cerebellum, and cortex associated with cognitive functions due to
anesthetic-induced toxicity early in life may cause cognitive decline later. Aquaporin 4 …