Benign prostatic hyperplasia (BPH) as the leading cause of urination disorder is still a
refractory disease, and there have no satisfied drugs or treatment protocols yet. With …

The immunomodulatory effect of divalent manganese cations (Mn2+), such as activation of
the cGAS− STING pathway or NLRP3 inflammasomes, positions them as adjuvants for …

Highlights•Collagen biomaterials to study fundamental processes underlying bone
regeneration.•Biomaterial design rules to induce endogenous production of cells and …

Inflammation plays a central role in immune response and macrophage activation. Emerging
studies demonstrate that along with proteins and genomic factors, noncoding RNA are …

Background Liver metastasis (LM) is a leading cause of cancer-related deaths in CRC
patients, whereas the associated mechanisms have not yet been fully elucidated. Therefore …

Extracellular vesicles (EVs) released by the helminths Dicrocoelium dendriticum and
Fasciola hepatica are important modulators of the host immune response, contributing to the …

The natural compound betulin has been extensively explored for its potential application as
an anticancer agent in recent years. Presently, the betulin compound was isolated from the …

Adenomyosis (AM) is a common gynecological disorder characterized by the presence of
endometrial glands and stroma within the uterine myometrium. It is associated with …

Ovarian tumor domain, ubiquitin aldehyde binding 1 (OTUB1), a deubiquitinating enzyme
known to regulate the stability of downstream proteins, has been reported to regulate …

Background/Objective: Tumor-associated macrophages (TAMs) produce an excessive
amount of cysteine proteases, and we aimed to study the effects of anticancer rhenium (I) …