Antimalarial Agents Derived from Metal‐Amodiaquine Complexes with Activity in Multiple Stages of the Plasmodium Life Cycle

L Colina‐Vegas, M da Cruz B. Silva… - … A European Journal, 2023 - Wiley Online Library
Malaria is the one of the deadliest infectious diseases worldwide. Chemically, quinolines are
excellent ligands for metal coordination and are deployed as drugs for malaria treatment …

Unlocking nitrogen compounds' promise against malaria: A comprehensive review

PV Kuthe, M Muzaffar‐Ur‐Rehman… - Archiv der …, 2024 - Wiley Online Library
Plasmodium parasites are the primary cause of malaria, leading to high mortality rates,
which require clinical attention. Many of the medications used in the treatment have resulted …

Conjugated carbon monoxide-releasing molecules have broad-spectrum antimicrobial activity

SS Mendes, M Sorg, CM Luís, D Fontinha… - Future Medicinal …, 2023 - Taylor & Francis
Aim: To test the antimicrobial effect of carbon monoxide-releasing molecules (CORMs)
conjugated with azoles on different microorganisms. Methods & results: We used broth …

Analysis of the interaction of antimalarial agents with Plasmodium falciparum glutathione reductase through molecular mechanical calculations

FHC Ferreira, LR Pinto, BA Oliveira, LV Daniel… - Journal of Molecular …, 2024 - Springer
Methods The drugs were tested as PfGR potential inhibitors via molecular docking on
AutoDock 4, which was performed based on the preoptimized structures in HF/3-21G-PCM …