The interactions between cancer cells and their microenvironment are crucial for malignant
progression, as they modulate invasion-related activities. Tumor-associated macrophages …

Ovarian cancer is an extremely lethal gynecologic disease; with the high-grade serous
subtype predominantly associated with poor survival rates. Lack of early diagnostic …

Tumor-associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion
and show strong expression of CD163 in breast cancer. We here investigated the …

Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …

The extracellular matrix (ECM) is a significant constituent of tumors, fulfilling various
essential functions such as providing mechanical support, influencing the microenvironment …

Macrophages are critical mediators of inflammation and important regulators of
developmental processes. As a key phagocytic cell type, macrophages evolved as part of …

Fibronectin 1 (FN1) is a glycoprotein found throughout the extracellular matrix that has a role
in the onset and progression of cancer. However, its immune relationship with gastric cancer …

We characterized the oxidative stress (OS) status by the levels of reduced/oxidized
glutathione (GSH/GSSG), malondialdehyde (MDA) and the mutagenic base 8-oxo-7′ 8 …

Prognosis of cholangiocarcinoma, a devastating liver epithelial malignancy characterized by
early invasiveness, remains very dismal, though its incidence has been steadily increasing …

Macrophages in the tumor microenvironment have a substantial impact on tumor
progression. Depending on the signaling environment in the tumor, macrophages can either …