Background Soft tissue sarcomas (STS) are a rare group of solid neoplasm including among
others liposarcoma, leiomyosarcoma (L-sarcoma) and undifferentiated pleomorphic …

Purpose Two types of macrophages are present in tumor microenvironment. M1
macrophages exhibit potent anti-tumor properties, while M2 macrophages play the pro …

The cancer tissue exists not as a single entity, but as a combination of different cellular
phenotypes which, taken together, dramatically contribute to the entirety of their ecosystem …

Cancer invasion of the surrounding tissue is a multiscale process of collective cell
movement that involves not only tumour cells but also other immune cells in the …

Successful establishment of a tumour relies on a cascade of interactions between cancer
cells and stromal cells within an evolving microenvironment. Both immune and nonimmune …

Pancreatic cancer (PC) remains a leading cause of mortality worldwide due to the absence
of early detection methods and the low success rates of traditional therapeutic strategies …

Due to the critical role of inflammation in nasopharyngeal carcinoma, we aim to investigate
the correlation between nasopharyngeal carcinoma prognosis and the levels of tumor …

Simple Summary We developed a “tumor-in-a-dish” experimental system to study the early
events favoring tumor growth and suppression of the immune response in metastatic …

Macrophages, the most heterogeneous cells of the hematopoietic system and the giant
eaters of the immune system that present either as tissue‐resident cells or infiltrated immune …

TGF-β1 is a pleiotropic factor exerting a strong regulatory role in several cell types, including
immune cells. In NK cells it profoundly alters the surface expression of crucial activating and …