The biomaterials-based three-dimensional (3D) cancer models enhance the investigation of
the mechanisms underpinning the cancer progression and metastasis. In vitro 3D tumor …

One of the earliest signs of dysregulation of the homeostatic process of fibrosis, associated
with pathology in chronic conditions such as rheumatoid arthritis, is the overexpression of …

Triple-negative breast cancer is the most aggressive and deadly subtype of breast cancer,
accounting for 30,000 cases annually in the US. While there are several clinical trials …

En torno al 90% de las muertes asociadas con cáncer se deben a la metástasis, proceso en
el que la intercomunicación dinámica existente entre el tumor y el microambiente tumoral es …

Introduction: High risk-human papillomavirus (HR-HPV) is a well-established aetiological
factor in a subset of oropharyngeal squamous cell carcinoma (OPSCC) that shows distinct …

Abstract Myeloid Derived Suppressor Cells (MDSCs) are a heterogeneous immune
population found within the tumour microenvironment (TME). We sought to explore the …

Purpose: Transforming growth factor-β (TGF-β) induces alternative macrophage activation
that favors tumor progression and immunosuppression. Meanwhile, paclitaxel (PTx) induces …

Over half of breast cancer related deaths are due to recurrence five or more years after initial
diagnosis and treatment. This latency suggests that a population of residual tumor cells can …

According to the differentiation potency related to the developmental hierarchy, stem cells
can be classified into embryonic stem cells, which give rise to all tissue types, and adult stem …

Tumour associated macrophages (TAMs) have been associated with prognosis in a wide
variety of tumours with most studies showing a high number of macrophages equating with …