L'échappement du cancer au système immunitaire fait intervenir deux mécanismes
principaux: une inhibition directe des cellules cytotoxiques par la tumeur et une inhibition …

Lung cancer stem cells arise from mutations in lung epithelial stem and progenitor cells that
reside in the conducting airways and alveolar bed. This chapter summarizes how the …

Cancer is a leading cause of death globally, and cancer management continues to pose a
great challenge to modern medicine. Major efforts have been made to obtain a …

Background: Neuroblastoma (NB) is a pediatric tumor in infants and young children. The
survival rate is only around 50 percent for high-risk NB despite advanced and intense multi …

ABSTRACT Although most recurrences (approximately 80%) occur in the first three years
after a curative resection, a recurrence of CRC can occur even ten years after the initial …

Lipoprotein lipase (LPL) is an extracellular lipase that hydrolyzes triglycerides and
phospholipids from circulating lipoproteins to promote the delivery of hydrolyzed lipids to …

Macrophages play critical roles in phagocytosis, inflammation, tissue repair, and tissue
damage. Traditionally, macrophages are divided into two subsets, classically activated …

Cancer develops in a complex tissue environment that aids tumor growth, invasion, and
metastasis. Tumor proliferation requires evasion of the immune response. To facilitate this …

Within this doctoral dissertation an enhancement to e-learning systems has been proposed
and the evaluation of its impact in the context of real learning was performed. The proposed …

Abstract Tumor-Associated Macrophages (TAM) are key orchestrators of the tumor
microenvironment, directly affecting neoplastic cell growth, neo-angiogenesis, extracellular …