Engineering dendritic cell vaccines to improve cancer immunotherapy

CR Perez, M De Palma - Nature communications, 2019 - nature.com
At the interface between the innate and adaptive immune system, dendritic cells (DCs) play
key roles in tumour immunity and hold a hitherto unrealized potential for cancer …

New insights of CCR7 signaling in dendritic cell migration and inflammatory diseases

W Hong, B Yang, Q He, J Wang, Q Weng - Frontiers in pharmacology, 2022 - frontiersin.org
CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events
in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph …

Breast cancer cell–derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function

J Wang, Q Wang, Y Guan, Y Sun… - The Journal of …, 2022 - Am Soc Clin Investig
Evidence suggests that increased microRNA-155 (miR-155) expression in immune cells
enhances antitumor immune responses. However, given the reported association of miR …

Pb exposure triggers MAPK-dependent inflammation by activating oxidative stress and miRNA-155 expression in carp head kidney

H Jing, Q Zhang, S Li, X Gao - Fish & Shellfish Immunology, 2020 - Elsevier
Lead (Pb) is a toxic heavy metal and an aquatic pollutant. Various amounts of heavy metals
are released into the environment through industrial discharge, causing excessive …

The role of miRNA in tumor immune escape and miRNA-based therapeutic strategies

Z Zhang, Q Huang, L Yu, D Zhu, Y Li, Z Xue… - Frontiers in …, 2022 - frontiersin.org
Tumor immune escape is a critical step in the malignant progression of tumors and one of
the major barriers to immunotherapy, making immunotherapy the most promising …

[HTML][HTML] Recent progress in the immunotherapy of hepatocellular carcinoma: Non-coding RNA-based immunotherapy may improve the outcome

F Afra, AA Mahboobipour, AS Farid, M Ala - Biomedicine & …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the second most lethal cancer and a leading cause of
cancer-related mortality worldwide. Immune checkpoint inhibitors (ICIs) significantly …

[HTML][HTML] The role of dendritic cells in tumor microenvironments and their uses as therapeutic targets

CW Kim, KD Kim, HK Lee - BMB reports, 2021 - ncbi.nlm.nih.gov
Dendritic cells (DC), which consist of several different subsets, specialize in antigen
presentation and are critical for mediating the innate and adaptive immune responses. DC …

Role of miR-155 in inflammatory autoimmune diseases: a comprehensive review

WD Xu, SY Feng, AF Huang - Inflammation Research, 2022 - Springer
Purpose MiR-155 is a member of the microRNAs (miRNAs) family and regulates gene
expression post-transcriptionally by binding to the 3'UTR of target mRNA. MiR-155 has a …

Breast cancer drug resistance: overcoming the challenge by capitalizing on MicroRNA and tumor microenvironment interplay

G Cosentino, I Plantamura, E Tagliabue, MV Iorio… - Cancers, 2021 - mdpi.com
Simple Summary The cross-talk between neoplastic cells and microenvironment is known to
play a crucial role in tumor development as well as in the phenomenon of resistance to …

The role of miR-155 in antitumor immunity

K Kalkusova, P Taborska, D Stakheev, D Smrz - Cancers, 2022 - mdpi.com
Simple Summary MiR-155 appears to be a significant regulator of immune responses
against tumors. The aim of this review is to provide an overview of miR-155 function in …