Ovarian hormones play an important role in pain perception, and are responsible, at least in
part, for the pain threshold differences between the sexes. Modulation of pain and its …

The underlying molecular basis of myalgic encephalomyelitis/chronic fatigue syndrome
(ME/CFS) is not well understood. Characterized by chronic, unexplained fatigue, a disabling …

We propose a framework for understanding and interpreting the pathophysiology of Myalgic
Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) that considers wider determinants …

Whilst parallels have been drawn between Long Covid and myalgic encephalomyelitis/
chronic fatigue syndrome (ME/CFS), there is a well-documented history of negative …

Background Post-exertional malaise (PEM) is considered a hallmark characteristic of
myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This may also apply to …

This is a comprehensive literature review of chronic fatigue syndrome (CFS). We provide a
description of the background, etiology, pathogenesis, diagnosis, and management …

Introduction People should have access to healthcare services that are effective, safe and
secure, patient‐centred, and coordinated and continuous. One group that has consistently …

A particular application of the biopsychosocial model is associated in peer-reviewed
literature and patient testimony with harms done to chronically ill and disabled people …

Fatigue is commonly reported in a variety of illnesses and has major impact on quality of life.
Chronic fatigue syndrome (CFS) is a debilitating syndrome of unknown etiology. The clinical …

Adult patients affected by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are
at an increased risk of death by suicide. Based on the scientific literature and our …