The literature of acute exacerbation of chronic obstructive pulmonary disease (COPD) is fast
expanding. This review focuses on several aspects of acute exacerbation of COPD …

Health status measurement is a common feature of studies in chronic obstructive pulmonary
disease (COPD). This review assesses recent evidence for the validity of these …

Background The Standards for the Diagnosis and Treatment of Patients with COPD
document 2004 updates the position papers on chronic obstructive pulmonary disease …

Since the last statements on pulmonary rehabilitation by the American Thoracic Society
(ATS; 1999) and the European Respiratory Society (ERS; 1997), there have been numerous …

The role of dynamic hyperinflation (DH) in exercise limitation in chronic obstructive
pulmonary disease (COPD) remains to be defined. We examined DH during exercise in 105 …

The aim of this study was to test the hypothesis that use of tiotropium, a new long-acting
anticholinergic bronchodilator, would be associated with sustained reduction in lung …

Currently available inhaled bronchodilators used as therapy for chronic obstructive
pulmonary disease (COPD) necessitate multiple daily dosing. The present study evaluates …

Tiotropium, a novel once-daily inhaled anticholinergic, has been shown to improve lung
function over a 24-h period. In order to extend these findings, health-outcomes were …

Changes in lung hyperinflation, dyspnea, and exercise endurance are important outcomes
in assessing therapeutic responses in chronic obstructive pulmonary disease (COPD) …

Chronic obstructive pulmonary disease (COPD) is a preventable and treatable lung disease
characterized by airflow limitation that is not fully reversible. In a significant proportion of …