Study objectives To examine and compare the efficacy and safety of salmeterol xinafoate, a
long-acting inhaledβ 2-adrenergic agonist, with inhaled ipratropium bromide and inhaled …

The clinical presentation of chronic obstructive pulmonary disease (COPD) is highly
variable, reflecting the interaction of a complex range of pathological changes including both …

This study examined the effects of bronchodilator-induced reductions in lung hyperinflation
on breathing pattern, ventilation and dyspnoea during exercise in chronic obstructive …

In patients with COPD, the maximal oxygen uptake (V˙ o 2) measured at peak exercise and
the 6-min walk distance (6MWD) have been associated with survival; however, no study has …

Fashions in ideas, like clothes, come and go. From approximately 1950–1980, physiological
research was seen as the key discipline in understanding lung disease and was at the …

Progressive activity-related dyspnea dominates the clinical presentation of patients afflicted
by chronic obstructive and restrictive lung diseases. This symptom invariably leads to activity …

The goals of therapy for chronic obstructive pulmonary disease include relieving symptoms,
improving abnormal physiology, and limiting complications, including abnormal gas …

Study objectives We have previously shown that tiotropium at 18 μg reduces lung
hyperinflation and dyspnea during exercise and improves exercise tolerance in patients with …

慢性阻塞性肺疾病(COPD) 是一种慢性呼吸系统疾病, 其主要特征为肺功能的缓慢减退及进行性
气流受限, 气流受限不完全可逆. 通过积极的预防和治疗可以有效缓解症状, 提高运动耐量 …

Lung-volume reduction surgery (LVRS) improves static lung elastic recoil in selected
patients with severe chronic obstructive pulmonary disease (COPD). This explains the …