A practical guide to chimerism analysis: review of the literature and testing practices worldwide

AG Blouin, F Ye, J Williams, M Askar - Human immunology, 2021 - Elsevier
Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …

Treatment of AML relapse after allo-HCT

JA Webster, L Luznik, I Gojo - Frontiers in Oncology, 2021 - frontiersin.org
With advances in allogeneic hematopoietic stem cell transplant (allo-HCT), disease relapse
has replaced transplant-related mortality as the primary cause of treatment failure for …

Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant

JJ Bednarski, C Zimmerman… - Blood, The Journal …, 2022 - ashpublications.org
Pediatric and young adult (YA) patients with acute myeloid leukemia (AML) who relapse
after allogeneic hematopoietic cell transplantation (HCT) have an extremely poor prognosis …

Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

The role of allogeneic hematopoietic stem cell transplantation in pediatric leukemia

M Algeri, P Merli, F Locatelli, D Pagliara - Journal of clinical medicine, 2021 - mdpi.com
Allogeneic hematopoietic stem cell transplantation (HSCT) offers potentially curative
treatment for many children with high-risk or relapsed acute leukemia (AL), thanks to the …

Opportunities for immunotherapy in childhood acute myeloid leukemia

AJ Lamble, SK Tasian - Blood Advances, 2019 - ashpublications.org
Clinical outcomes for children with acute myeloid leukemia (AML) have improved minimally
during the past 4 decades despite maximally intensive chemotherapy, hematopoietic stem …

Chronic graft‐versus‐host disease: Current management paradigm and future perspectives

H Mawardi, SK Hashmi, S Elad, M Aljurf… - Oral diseases, 2019 - Wiley Online Library
Introduction The field of allogeneic hematopoietic cell transplantation (allo‐HCT) began in
the 1950s, and despite a seven decade history of remarkable clinical advances, graft‐versus …

Comparison of outcomes after donor lymphocyte infusion with or without prior chemotherapy for minimal residual disease in acute leukemia/myelodysplastic …

XD Mo, XH Zhang, LP Xu, Y Wang, CH Yan… - Annals of …, 2017 - Springer
The efficacy of donor lymphocyte infusion (DLI) without chemotherapy was investigated and
compared with that of chemotherapy prior to DLI (Chemo-DLI) in patients who were minimal …

[HTML][HTML] Allogeneic hematopoietic cell transplantation in multiple myeloma: focus on longitudinal assessment of donor chimerism, extramedullary disease, and high …

L Rasche, C Röllig, G Stuhler, S Danhof… - Biology of Blood and …, 2016 - Elsevier
Although generally not applied as first-line treatment of multiple myeloma, allogeneic
hematopoietic cell transplantation (allo-SCT) can still be chosen as ultimate escalation …

The impact of total body irradiation‐based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic …

BD Friend, M Bailey‐Olson, A Melton… - Pediatric blood & …, 2020 - Wiley Online Library
Introduction Total body irradiation (TBI)‐based conditioning is the standard of care in the
treatment of acute lymphoblastic leukemia (ALL) that requires allogeneic hematopoietic …