(−)-Epicatechin gallate prevented atherosclerosis by reducing abnormal proliferation of VSMCs and oxidative stress of AML 12 cells

J Yu, H Song, L Zhou, S Wang, X Liu, L Liu, Y Ma, L Li… - Cellular …, 2024 - Elsevier
Epicatechin gallate (ECG) is beneficial to the treatment of cardiovascular diseases (CVDs),
especially atherosclerosis (AS) through antioxidant stress, but there is a lack of detailed …

Network pharmacology, molecular docking, and in vitro experimental verification of the mechanism of Guanxining in treating diabetic atherosclerosis

W Wang, S Wang, Y Li, M Zhu, Q Xu, B Luo… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Guanxinning (GXN) tablet is a patented traditional
Chinese medicine widely used to prevent and treat cardiovascular diseases. However, its …

Morroniside attenuates podocytes lipid deposition in diabetic nephropathy: A network pharmacology, molecular docking and experimental validation study

Y Chen, M Chen, W Zhu, Y Zhang, P Liu, P Li - International …, 2024 - Elsevier
Background Dysregulation of lipid metabolism is a key factor influencing the progression of
diabetic nephropathy (DN). Morroniside (MOR) is a major active compound isolated from the …

Yigansan ameliorates maternal immune activation-induced autism-like behaviours by regulating the IL-17A/TRAF6/MMP9 pathway: Network analysis and …

L Fan, X Zeng, Y Jiang, D Zheng, H Wang, Q Qin, M Li… - Phytomedicine, 2024 - Elsevier
Background Maternal immune activation (MIA) is a significant factor inducing to autism
spectrum disorder (ASD) in offspring. The fundamental principle underlying MIA is that …

Incorporating Network Pharmacology and Experimental Validation to Identify Bioactive Compounds and Potential Mechanisms of Digitalis in Treating Anaplastic …

L Zhu, R Liang, Y Guo, Y Cai, F Song, Y Hu, Y Liu… - ACS …, 2024 - ACS Publications
Anaplastic thyroid cancer (ATC) is one of the most lethal malignant tumors for which there is
no effective treatment. There are an increasing number of studies on herbal medicine for …

Berberine alleviates neuroinflammation by downregulating NFkBκκNF/LCN2 pathway in sepsis-associated encephalopathy: Network pharmacology, bioinformatics …

H Gong, Y Xia, G Jing, M Yuan, H Zhou, D Wu… - International …, 2024 - Elsevier
Background Sepsis refers to a systemic inflammatory response caused by infection,
involving multiple organs. Sepsis-associated encephalopathy (SAE), as one of the most …

Natural flavonoid glycosides Chrysosplenosides I & A rejuvenate intestinal stem cell aging via activation of PPARγ signaling

J Ye, L Yan, Y Yuan, F Fu, L Yuan, X Fan, J Zhou… - Life …, 2024 - academic.oup.com
The decline in intestinal stem cell (ISC) function is a hallmark of aging, contributing to
compromised intestinal regeneration and increased incidence of age-associated diseases …

A novel herbal aromatic essential oil for treating Chemotherapy-Induced Nausea and Vomiting: a mass spectrometry and network pharmacology study of the …

M Zhan, Y Sun, J Yan, Q Zhang, L Han, P Zhang, H Lin… - 2024 - researchsquare.com
Objectives: This study aimed to investigate the substance basis and pharmacological
mechanism of Dingxiang Shidi Decoction in preventing and treating Chemotherapy-Induced …

[PDF][PDF] Journal of Experimental and Clinical Application of Chinese Medicine

T Chen, X Zhang, W Zhang, Y Liu - Journal of Experimental and …, 2024 - exploverpub.com
The complex syndrome of obesity is a complex syndrome associated with various metabolic
disorders, poses significant threats to human health. Many weight loss medications have the …

[HTML][HTML] Exploring the Potential of Lotus Leaf and Its Bioactive Compounds for Anti-obesity Interventions

L Chen, X Zhang, W Zhang… - Journal of Experimental …, 2024 - ojs.exploverpub.com
The complex syndrome of obesity is a complex syndrome associated with various metabolic
disorders, poses significant threats to human health. Many weight loss medications have the …