[HTML][HTML] Drug-induced oxidative stress in cancer treatments: Angel or devil?
H Jiang, J Zuo, B Li, R Chen, K Luo, X Xiang, S Lu… - Redox Biology, 2023 - Elsevier
Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …
most significant biological events in cancer progression. Cancer cells generally represent a …
Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next‐Generation Therapeutics
Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …
interest in recent years owing to their ability to replace natural enzymes in various …
NOX dependent ROS generation and cell metabolism
T Pecchillo Cimmino, R Ammendola… - International Journal of …, 2023 - mdpi.com
Reactive oxygen species (ROS) represent a group of high reactive molecules with dualistic
natures since they can induce cytotoxicity or regulate cellular physiology. Among the ROS …
natures since they can induce cytotoxicity or regulate cellular physiology. Among the ROS …
Reactive oxygen species (ROS), oxygen radicals and antioxidants: Where are we now, where is the field going and where should we go?
B Halliwell - Biochemical and biophysical research communications, 2022 - Elsevier
The field of oxygen free radicals, antioxidants and reactive oxygen species (ROS) has
exploded in the past few decades, and BBRC has published several seminal papers. ROS …
exploded in the past few decades, and BBRC has published several seminal papers. ROS …
[HTML][HTML] New treatment paradigms in primary biliary cholangitis
C Levy, M Manns, G Hirschfield - Clinical Gastroenterology and Hepatology, 2023 - Elsevier
Primary biliary cholangitis (PBC) is an archetypal autoimmune disease. Chronic lymphocytic
cholangitis is associated with interface hepatitis, ductopenia, cholestasis, and progressive …
cholangitis is associated with interface hepatitis, ductopenia, cholestasis, and progressive …
From imbalance to impairment: the central role of reactive oxygen species in oxidative stress-induced disorders and therapeutic exploration
Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …
health issues, including metabolic problems, cancers, and neurological conditions. Our …
Mechanisms regulating neutrophil responses in immunity, allergy, and autoimmunity
Neutrophil granulocytes, or neutrophils, are the most abundant circulating leukocytes in
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …
[HTML][HTML] Targeting DNA methylation and demethylation in diabetic foot ulcers
JY Deng, XQ Wu, WJ He, X Liao, M Tang… - Journal of Advanced …, 2023 - Elsevier
Background Poor wound healing is a significant complication of diabetes, which is
commonly caused by neuropathy, trauma, deformities, plantar hypertension and peripheral …
commonly caused by neuropathy, trauma, deformities, plantar hypertension and peripheral …
Elexacaftor/tezacaftor/ivacaftor corrects monocyte microbicidal deficiency in cystic fibrosis
L Cavinato, FR Luly, V Pastore… - European …, 2023 - Eur Respiratory Soc
Background Cystic fibrosis (CF), which is caused by mutations in the CF transmembrane
conductance regulator (CFTR), is characterised by chronic bacterial lung infection and …
conductance regulator (CFTR), is characterised by chronic bacterial lung infection and …
[HTML][HTML] NOX-induced oxidative stress is a primary trigger of major neurodegenerative disorders
Y Zilberter, DR Tabuena, M Zilberter - Progress in Neurobiology, 2023 - Elsevier
Neurodegenerative diseases (NDDs) causing cognitive impairment and dementia are
difficult to treat due to the lack of understanding of primary initiating factors. Meanwhile …
difficult to treat due to the lack of understanding of primary initiating factors. Meanwhile …