Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield

T Isah, S Umar, A Mujib, MP Sharma… - Plant Cell, Tissue and …, 2018 - Springer
Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …

Contribution of endophytes towards improving plant bioactive metabolites: a rescue option against red-taping of medicinal plants

S Tsipinana, S Husseiny, KA Alayande… - Frontiers in Plant …, 2023 - frontiersin.org
Medicinal plants remain a valuable source for natural drug bioprospecting owing to their
multi-target spectrum. However, their use as raw materials for novel drug synthesis has been …

Harnessing plant biotechnology-based strategies for in vitro galanthamine (GAL) biosynthesis: A potent drug against Alzheimer's disease

H Kaur, S Chahal, P Jha, MM Lekhak… - Plant Cell, Tissue and …, 2022 - Springer
Medicinal plants are important for improving human health and represent an essential pool
for the identification of novel pharmacological leads. Plant-derived biomolecules have …

Synergism of m-topolin with auxin and cytokinin enhanced micropropagation of Maytenus emarginata

JK Shekhawat, MK Rai, NS Shekhawat… - In Vitro Cellular & …, 2021 - Springer
A synergistic effect of meta-topolin (m T) with auxin and cytokinin has been applied to
stimulate large-scale shoot regeneration from Maytenus emarginata mature tree nodal …

[HTML][HTML] Unlocking the genetic potential: Strategies for enhancing secondary metabolite biosynthesis in plants

NM Al Aboud - Journal of the Saudi Society of Agricultural Sciences, 2024 - Elsevier
The majority of secondary metabolites (SMs) are derived from plant defense, and they are
crucial for the research and development of novel drugs. This article is an extensive …

Efficient plant regeneration from embryogenic cell suspension cultures of Euonymus alatus

HA Woo, SS Ku, EY Jie, HR Kim, HS Kim, HS Cho… - Scientific Reports, 2021 - nature.com
To establish an efficient plant regeneration system from cell suspension cultures of
Euonymus alatus, embryogenic callus formation from immature embryos was investigated …

Pectinases Secretion by Saccharomyces cerevisiae: Optimization in Solid-State Fermentation and Identification by a Shotgun Proteomics Approach

MM Takeyama, MC de Carvalho, HS Carvalho… - Molecules, 2022 - mdpi.com
A sequential design strategy was applied to optimize the secretion of pectinases by a
Saccharomyces cerevisiae strain, from Brazilian sugarcane liquor vat, on passion fruit …

Biotechnology based strategies for secondary metabolites enhancement: a review

Shruti, N Bharadvaja - Vegetos, 2023 - Springer
The primary sources of essential secondary metabolites (SMs) which are crucial for drug
discovery and development are derived from plants. Plants frequently utilize these …

Friedelin in Maytenus ilicifolia Is Produced by Friedelin Synthase Isoforms

TB Alves, TM Souza-Moreira, SR Valentini, CF Zanelli… - Molecules, 2018 - mdpi.com
Triterpenes are interesting compounds because they play an important role in cell
homeostasis and a wide variety exhibiting defense functions is produced by plant secondary …

Metaproteomics reveals the structural and functional diversity of Dermatocarpon miniatum (L.) W. Mann. Microbiota

J Ullah, Z Khanum, IA Khan, AN Khalid, SG Musharraf… - Fungal biology, 2021 - Elsevier
Metaproteomics is a strategy to understand the taxonomy, functionality and metabolic
pathways of the microbial communities. The relationship among the symbiotic microbiota in …