Harnessing non-destructive 3D pathology

JTC Liu, AK Glaser, K Bera, LD True… - Nature biomedical …, 2021 - nature.com
High-throughput methods for slide-free three-dimensional (3D) pathological analyses of
whole biopsies and surgical specimens offer the promise of modernizing traditional …

The impact of toxic metal bioaccumulation on colorectal cancer: unravelling the unexplored connection

R Bonfiglio, R Sisto, S Casciardi, V Palumbo… - Science of the Total …, 2023 - Elsevier
Colorectal cancer is a major public health concern, with increasing incidence and mortality
rates worldwide. Environmental factors, including exposure to toxic metals, such as lead …

Radiolabeled PET/MRI nanoparticles for tumor imaging

E Forte, D Fiorenza, E Torino… - Journal of clinical …, 2019 - mdpi.com
The development of integrated positron emission tomography (PET)/magnetic resonance
imaging (MRI) scanners opened a new scenario for cancer diagnosis, treatment, and follow …

[HTML][HTML] Aluminium bioaccumulation in colon cancer, impinging on epithelial-mesenchymal-transition and cell death

R Bonfiglio, R Sisto, S Casciardi, V Palumbo… - Science of The Total …, 2024 - Elsevier
We investigated the presence of aluminium (Al) in human colon cancer samples and its
potential association with biological processes involved in cancer progression, such as …

Investigating the potential of oncolytic viruses for cancer treatment via MSC delivery

HEG Ghaleh, G Vakilzadeh, A Zahiri… - Cell Communication and …, 2023 - Springer
Mesenchymal stem cells (MSCs) have attracted considerable interest as a promising
approach for cancer treatment due to their ability to undergo tumor-trophic migration. MSCs …

Modifications of behavior and inflammation in mice following transplant with fecal microbiota from children with autism

E Avolio, I Olivito, E Rosina, L Romano, T Angelone… - Neuroscience, 2022 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder displaying the
modification of complex human behaviors, characterized by social interaction impairments …

A model combining pretreatment MRI radiomic features and tumor-infiltrating lymphocytes to predict response to neoadjuvant systemic therapy in triple-negative …

JE Jimenez, A Abdelhafez, EA Mittendorf… - European Journal of …, 2022 - Elsevier
Purpose We aimed to develop a predictive model based on pretreatment MRI radiomic
features (MRIRF) and tumor-infiltrating lymphocyte (TIL) levels, an established prognostic …

[PDF][PDF] Molecular imaging and the PD-L1 pathway: from bench to clinic

D Leung, S Bonacorsi, RA Smith, W Weber… - Frontiers in …, 2021 - frontiersin.org
Programmed death-1 (PD-1) and programmed death ligand 1 (PD-L1) inhibitors target the
important molecular interplay between PD-1 and PD-L1, a key pathway contributing to …

Cold formalin fixation guarantees DNA integrity in formalin fixed paraffin embedded tissues: premises for a better quality of diagnostic and experimental pathology with …

E Berrino, L Annaratone, U Miglio, E Maldi… - Frontiers in …, 2020 - frontiersin.org
Formalin fixation and paraffin embedding (FFPE) represent the standard method to preserve
tissue specimens for diagnostic pathology, however formalin fixation induces severe …

Imaging response evaluation after neoadjuvant treatment in soft tissue sarcomas: Where do we stand?

N Gennaro, S Reijers, A Bruining, C Messiou… - Critical Reviews in …, 2021 - Elsevier
Soft tissue sarcomas (STS) represent a broad family of rare tumours for which surgery with
radiotherapy represents first-line treatment. Recently, neoadjuvant chemo-radiotherapy has …