High altitude pulmonary edema (HAPE) occurs in individuals rapidly ascending at altitudes
greater than 2,500 m within one week of arrival. HAPE is characterized by orthopnea …

Decreased oxygen saturation (SO2) at high altitude is associated with potentially life-
threatening diseases, eg, high-altitude pulmonary edema. Wearable devices that allow …

This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …

Reabsorption of excess alveolar fluid is driven by vectorial Na+-transport across alveolar
epithelium, which protects from alveolar flooding and facilitates gas exchange. Hypoxia …

Small, Elan, Caleb Phillips, William Bunzel, Lakota Cleaver, Nishant Joshi, Laurel Gardner,
Rony Maharjan, and James Marvel. Prior ambulatory mild coronavirus disease 2019 does …

Background It is postulated that lack of hypoxic ventilatory response is a predictor for AMS.
End-tidal carbon dioxide (ETCO 2) is an accurate, noninvasive surrogate measure of …

Hypoxia-related microRNAs (miRNAs) are involved in the pathogenesis of various diseases.
Because potential variations in miRNA expression mediated by hypoxic lung injury at high …

The yak (Bos grunniens) is a species adapted to the hypoxic environment in the plateau
area. The heart is a hypoxia‐sensitive organ involved in this adaptation. Herein, we used …

Small, Elan, Nicholas Juul, David Pomeranz, Patrick Burns, Caleb Phillips, Mary Cheffers,
and Grant S. Lipman. Predictive capacity of pulmonary function tests for acute mountain …

Background: With increase in the footfall to mountainous areas for occupational and
recreational purposes, tackling the burden of high-altitude illnesses is a growing public …