Fluoroquinolones hybrid molecules as promising antibacterial agents in the fight against antibacterial resistance

IA Lungu, OL Moldovan, V Biriș, A Rusu - Pharmaceutics, 2022 - mdpi.com
The emergence of bacterial resistance has motivated researchers to discover new
antibacterial agents. Nowadays, fluoroquinolones keep their status as one of the essential …

1, 2, 3-Triazole-containing hybrids with potential antibacterial activity against ESKAPE pathogens

C Deng, H Yan, J Wang, K Liu, B Liu, Y Shi - European Journal of …, 2022 - Elsevier
ESKAPE pathogens, as priority 1 and 2 pathogens, are prevalent infectious agents
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …

An increase in erythromycin resistance in methicillin-susceptible Staphylococcus aureus from blood correlates with the use of macrolide/lincosamide/streptogramin …

A El Mammery, E Ramírez de Arellano… - Frontiers in …, 2023 - frontiersin.org
Objectives To describe and analyse erythromycin resistance trends in blood isolates of
Staphylococcus aureus (EARS-Net Spain, 2004–2020) and the association of these trends …

New prenylated indole diketopiperazine alkaloids and polyketides from the mangrove-derived fungus Penicillium sp

R Huo, J Zhang, S Niu, L Liu - Frontiers in Marine Science, 2022 - frontiersin.org
Two new prenylated indole diketopiperazine alkaloids (PIDAs) penicamides A and B (1 and
2) and three new polyketides penicinones A− C (6− 8), along with four known compounds …

Sulfur-containing benzofurans and α-pyrones from the mangrove-derived fungus Talaromyces sp. WHUF0341

R Zhang, J Zhang, R Huo, Y Xue, K Hong… - Frontiers in Marine …, 2022 - frontiersin.org
Two new sulfur-containing benzofurans, talarobenzofurans A and B (1 and 2), one new
benzofuran talarobenzofuran C (3) and two new α-pyrones talaropyrones A and B (5 and 6) …

The emergence of novel macrolide resistance island in Macrococcus caseolyticus and Staphylococcus aureus of food origin

F Zhang, S Wu, J Dai, J Huang, J Zhang, M Zhao… - International Journal of …, 2023 - Elsevier
Food-derived Staphylococcaceae species with severe antimicrobial resistance, especially
Staphylococcus aureus, is a major threat to public health. Macrococcus caseolyticus (M …

Design and synthesis of novel macrolones bridged with linkers from 11, 12-positions of macrolides

XP Liu, W Lv, F Zhao, J Ding, JR Zhang, F Xue… - Bioorganic & Medicinal …, 2022 - Elsevier
Resistance to telithromycin and off-target effects associated with the metabolic instability
present serious and challenging problems for the development of novel macrolides. Herein …

双环克拉霉素衍生物的合成及抗肿瘤活性研究.

孙俊, 王展, 潘佳彤, 关奇, 张为革… - Journal of Shenyang …, 2024 - search.ebscohost.com
目的设计并合成一系列3-氧代-8ꎬ9ꎻ10ꎬ11-双脱水-N-去甲克拉霉素衍生物ꎬ
进行体外抗肿瘤活性研究ꎮ 方法以克拉霉素为起始原料ꎬ 经脱除克拉定糖, 羟基保护, 氧化 …