Exercise Facilitates the M1-to-M2 Polarization of Microglia by Enhancing Autophagy via the BDNF/AKT/mTOR Pathway in Neuropathic Pain.

J Bai, B Geng, X Wang, S Wang, Q Yi, Y Tang… - Pain …, 2022 - europepmc.org
Background In neuropathic pain following peripheral nerve injury, microglia are rapidly
activated and accumulated in the spinal cord. Physical exercise can alleviate neuropathic …

Neuropathic pain: sensory nerve injury or motor nerve injury?

XG Liu, RP Pang, LJ Zhou, XH Wei, Y Zang - Translational Research in …, 2016 - Springer
Peripheral nerve injury often induces chronic neuropathic pain. Peripheral nerve is
consisted of sensory fibers and motor fibers, it is questioned injury to which type of fibers is …

Localised delivery of quercetin by thermo-sensitive PLGA-PEG-PLGA hydrogels for the treatment of brachial plexus avulsion

C Huang, C Fu, ZP Qi, WL Guo, D You… - Artificial cells …, 2020 - Taylor & Francis
Accumulating evidence indicates that oxidative stress and inflammation are implicated in
brachial plexus avulsion (BPA). Quercetin has anti-inflammatory, anti-oxidant, anti-apoptotic …

Alterations in the BDNF–mTOR signaling pathway in the spinal cord contribute to hyperalgesia in a rodent model of chronic restraint stress

N Huang, C Yang, D Hua, S Li, G Zhan, N Yang, A Luo… - Neuroscience, 2019 - Elsevier
Stress is a non-specific, systemic, physiological response of the body to strong internal and
external environmental stimuli. Accumulating evidence has suggested that stress …

Effect of lentiviral vector-mediated overexpression of hypoxia-inducible factor 1 alpha delivered by pluronic F-127 hydrogel on brachial plexus avulsion in rats

T Wang, LN Zeng, Z Zhu, YH Wang… - Neural regeneration …, 2019 - journals.lww.com
Brachial plexus avulsion often results in massive motor neuron death and severe functional
deficits of target muscles. However, no satisfactory treatment is currently available. Hypoxia …

Effects of Ozone on Hippocampus BDNF and Fos Expressions in Rats with Chronic Compression of Dorsal Root Ganglia

L Zhu, Y Wang, X Lin, X Zhao… - BioMed Research …, 2021 - Wiley Online Library
The effects of ozone on hippocampal expression levels of brain‐derived neurotrophic factor
(BDNF) and c‐fos protein (Fos) were evaluated in rats with chronic compression of dorsal …

Exogenous brain-derived neurotrophic factor relieves pain symptoms of diabetic rats by reducing excitability of dorsal root ganglion neurons

L Li, T Yu, L Yu, H Li, Y Liu, D Wang - International Journal of …, 2016 - Taylor & Francis
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes lacking of
effective treatments. Enhanced excitability of dorsal root ganglion (DRG) neuron plays a …

[HTML][HTML] 外源性脑源神经营养因子降低糖尿病大鼠痛阈的机制研究

于婷, 成洪聚, 辛青, 许飞, 李雷 - 济宁医学院学报, 2019 - jnyxy.cnjournals.org
目的探讨外源性脑源神经营养因子(BDNF) 及其高亲和力受体酪氨酸激酶受体B (TrkB)
对糖尿病周围神经病变(DPN) 大鼠的痛觉过敏症状的作用及其机制. 方法利用链脲佐菌素(STZ) …

Contribution of capsaicin-sensitive primary afferents to mechanical hyperalgesia induced by ventral root transection in rats: the possible role of BDNF

W Li, JX Wang, ZH Zhou, Y Lu, XQ Li, BJ Liu… - Neurological …, 2016 - Taylor & Francis
Objective: A recent study showed that brain-derived neurotrophic factor (BDNF) may play a
role in the development of the neuropathic pain resulting from injury to motor efferent fibres …

[引用][C] 郁金提取物对CCI 模型大鼠痛觉行为及BDNF 表达的影响

厉飞, 裘涛, 胡娅娜, 陶水良 - 中国中医急症, 2015