Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

To successfully negotiate the developmental transition between youth and adulthood,
adolescents must maneuver this often stressful period while acquiring skills necessary for …

About one million suicides and ten million suicide attempts occur worldwide each year.
Suicide is not simply a response to stress, but generally a complication of a psychiatric …

Cortical growth and remodeling continues from birth through youth and adolescence to
stable adult levels changing slowly into senescence. There are critical periods of cortical …

Background: The serotonin-1A (5HT1A) receptor system has been implicated in the
pathophysiology of major depression by postmortem studies of suicide victims and …

Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric
diseases of late life may contribute to behavioral changes commonly observed in the elderly …

Abstract Rationale Serotonin (5-HT) neurotransmission is intimately linked to anxiety and
depression and a diverse body of evidence supports the involvement of the main inhibitory …

Background Pharmacological and postmortem investigations suggest that patients with
major depressive disorder have alterations in function or density of brain serotonin 1A (5-HT …

Alzheimer's disease (AD) is one of the major neurodegenerative diseases that deteriorates
cognitive functions and primarily affects associated brain regions involved in learning and …

All of the serotonin-producing neurons of the mammalian brain are located in 10 nuclei in
the mid-and hindbrain regions. The cells of the rostal nuclei project to almost every area of …