The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …

Immunoglobulin A vasculitis (IgAV), also referred to as Henoch-Schönlein purpura, is the
most common form of childhood vasculitis. The pathogenesis of IgAV is still largely …

Vascular endothelial cells normally perform several key homeostatic functions such as
keeping blood fluid, regulating blood flow, regulating macromolecule and fluid exchange …

In recent years, the relationship between inflammation and thrombosis has been deeply
investigated and it is now clear that immune and coagulation systems are functionally …

A proportion of COVID-19 reconvalescent patients develop post-COVID-19 syndrome (PCS)
including a subgroup fulfilling diagnostic criteria of Myalgic encephalomyelitis/Chronic …

Vascular endothelial injury in systemic sclerosis (SSc) includes a spectrum of changes that
involve predominantly the microcirculation and arterioles. The pathologic changes in the …

Inflammatory neuropathies encompass groups of heterogeneous disorders characterized by
pathogenic immune-mediated hematogenous leukocyte infiltration of peripheral nerves …

Right ventricular failure (RVF) is the main determinant of mortality in patients with pulmonary
arterial hypertension (PAH). Although the exact pathophysiology underlying RVF remains …

Anti-endothelial cell antibodies (AECA) are a heterogeneous class of antibodies whose role
in the pathogenesis of autoimmune diseases with vascular involvement has been …

Objective In neuromyelitis optica (NMO), the destruction of the blood–brain barrier (BBB) has
been considered to be the first step of the disease process. It is unclear whether sera from …