Alveolar lipids in pulmonary disease. A review

CW Agudelo, G Samaha, I Garcia-Arcos - Lipids in health and disease, 2020 - Springer
Lung lipid metabolism participates both in infant and adult pulmonary disease. The lung is
composed by multiple cell types with specialized functions and coordinately acting to meet …

In vitro models to study human lung development, disease and homeostasis

AJ Miller, JR Spence - Physiology, 2017 - journals.physiology.org
The main function of the lung is to support gas exchange, and defects in lung development
or diseases affecting the structure and function of the lung can have fatal consequences …

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

B Spix, ES Butz, CC Chen, AS Rosato, R Tang… - Nature …, 2022 - nature.com
Lung emphysema and chronic bronchitis are the two most common causes of chronic
obstructive pulmonary disease. Excess macrophage elastase MMP-12, which is …

Interactions of particulate matter and pulmonary surfactant: Implications for human health

F Wang, J Liu, H Zeng - Advances in colloid and interface science, 2020 - Elsevier
Particulate matter (PM), which is the primary contributor to air pollution, has become a
pervasive global health threat. When PM enters into a respiratory tract, the first body tissues …

Lung surfactant for pulmonary barrier restoration in patients with COVID-19 pneumonia

U Mirastschijski, R Dembinski, K Maedler - Frontiers in medicine, 2020 - frontiersin.org
Corona virus SARS-CoV-2 has already spread around the whole world and is currently, with
no vaccine available yet, unstoppable. As per today, COVID-19 affects more than 3,000,000 …

Newborn infants' hair cortisol levels reflect chronic maternal stress during pregnancy

B Romero-Gonzalez, RA Caparros-Gonzalez… - PloS one, 2018 - journals.plos.org
Cortisol obtained from hair samples represents a retrospective biomarker of chronic stress
experienced by the subject in previous months. Although hair cortisol levels have been used …

The role of pulmonary surfactants in the treatment of acute respiratory distress syndrome in COVID-19

S Wang, Z Li, X Wang, S Zhang, P Gao… - Frontiers in …, 2021 - frontiersin.org
Lung alveolar type-II (AT-II) cells produce pulmonary surfactant (PS), consisting of proteins
and lipids. The lipids in PS are primarily responsible for reducing the air-fluid surface tension …

Physicochemical properties of nanoparticles affecting their fate and the physiological function of pulmonary surfactants

Q Liu, J Guan, R Song, X Zhang, S Mao - Acta biomaterialia, 2022 - Elsevier
Pulmonary drug delivery has drawn great attention due to its targeted local lung action,
reduced side effects, and ease of administration. However, inhaled nanoparticles (NPs) …

[HTML][HTML] Restoring pulmonary surfactant membranes and films at the respiratory surface

M Echaide, C Autilio, R Arroyo, J Perez-Gil - Biochimica et Biophysica Acta …, 2017 - Elsevier
Pulmonary surfactant is a complex of lipids and proteins assembled and secreted by the
alveolar epithelium into the thin layer of fluid coating the respiratory surface of lungs. There …

Macrophages modulate stiffness-related foreign body responses through plasma membrane deformation

Y Ni, H Qi, F Zhang, S Jiang, Q Tang… - Proceedings of the …, 2023 - National Acad Sciences
Implants are widely used in medical applications and yet macrophage-mediated foreign
body reactions caused by implants severely impact their therapeutic effects. Although the …