The genetic architecture of quantitative traits

TFC Mackay - Annual review of genetics, 2001 - annualreviews.org
▪ Abstract Phenotypic variation for quantitative traits results from the segregation of alleles at
multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and …

Estimating FST and kinship for arbitrary population structures

A Ochoa, JD Storey - PLoS genetics, 2021 - journals.plos.org
F ST and kinship are key parameters often estimated in modern population genetics studies
in order to quantitatively characterize structure and relatedness. Kinship matrices have also …

Use of major quantitative trait loci to improve grain yield of rice

L GUO, G YE - Rice science, 2014 - Elsevier
Further improvement of rice productivity remains a challenge. Breeding is perceived as an
important option to increase rice yield. However, the genetic progress of grain yield in most …

Mapping quantitative trait loci in complex pedigrees: a two-step variance component approach

AW George, PM Visscher, CS Haley - Genetics, 2000 - academic.oup.com
There is a growing need for the development of statistical techniques capable of mapping
quantitative trait loci (QTL) in general outbred animal populations. Presently used variance …

MCQTL: multi-allelic QTL mapping in multi-cross design

MF Jourjon, S Jasson, J Marcel, B Ngom… - …, 2005 - academic.oup.com
The aim of the MCQTL software package is to perform QTL mapping in multi-cross designs.
It allows the analysis of the usual populations derived from inbred lines and can link the …

Mapping epistatic quantitative trait loci with one-dimensional genome searches

JL Jannink, R Jansen - Genetics, 2001 - academic.oup.com
The discovery of epistatically interacting QTL is hampered by the intractability and low power
to detect QTL in multidimensional genome searches. We describe a new method that maps …

Using quantitative trait loci results to discriminate among crosses on the basis of their progeny mean and variance

S Zhong, JL Jannink - Genetics, 2007 - academic.oup.com
To develop inbred lines, parents are crossed to generate segregating populations from
which superior inbred progeny are selected. The value of a particular cross thus depends on …

Using mating designs to uncover QTL and the genetic architecture of complex traits

KJF Verhoeven, JL Jannink, LM McIntyre - Heredity, 2006 - nature.com
Abstract Analysis of quantitative trait loci (QTL) affecting complex traits is often pursued in
single-cross experiments. For most purposes, including breeding, some assessment is …

How do the type of QTL effect and the form of the residual term influence QTL detection in multi-parent populations? A case study in the maize EU-NAM population

V Garin, V Wimmer, S Mezmouk, M Malosetti… - Theoretical and Applied …, 2017 - Springer
Key message In the QTL analysis of multi-parent populations, the inclusion of QTLs with
various types of effects can lead to a better description of the phenotypic variation and …

Analytical approaches and population types for finding and utilizing QTL in complex plant populations

CH Sneller, DE Mather, S Crepieux - Crop science, 2009 - Wiley Online Library
In the past decade plant geneticists began using complex plant populations to identify QTL
by association analysis, and the practice is becoming commonplace. Plant populations …