Enabling technologies for personalized and precision medicine
Individualizing patient treatment is a core objective of the medical field. Reaching this
objective has been elusive owing to the complex set of factors contributing to both disease …
objective has been elusive owing to the complex set of factors contributing to both disease …
Harnessing CURATE. AI as a digital therapeutics platform by identifying N‐of‐1 learning trajectory profiles
Conventional therapeutic interventions, which range from drug treatment to learning and
training regimens, are often given at a fixed dose/intensity. This often leads to sub‐optimal …
training regimens, are often given at a fixed dose/intensity. This often leads to sub‐optimal …
Improving biopharmaceutical safety through verification-based quality control
YB Yu, MB Taraban, W Wang, KT Briggs - Trends in biotechnology, 2017 - cell.com
Biopharmaceuticals and small-molecule drugs have different approval pathways but the
same quality control (QC) paradigm, where the quality of released but untested units is …
same quality control (QC) paradigm, where the quality of released but untested units is …
Recent advances in precision medicine for individualized immunosuppression
S Fu, A Zarrinpar - Current opinion in organ transplantation, 2020 - journals.lww.com
The integration of advanced computing tools, such as artificial neural networks and machine
learning, with genome sequencing has led to intriguing findings on individual or group …
learning, with genome sequencing has led to intriguing findings on individual or group …
Advancing personalized treatment of Alzheimer's disease: a call for the N-of-1 trial design
JE Galvin - Future Neurology, 2018 - Taylor & Francis
There has not been a new treatment for Alzheimer's disease (AD) for over a decade, with a
large number of Phase II/III randomized clinical trials failing. Randomized clinical trials …
large number of Phase II/III randomized clinical trials failing. Randomized clinical trials …
Phenotypic response and personalized medicine in liver cancer and transplantation: approaches to complex systems
A Zarrinpar, UB Kim, V Boominathan - Advanced Therapeutics, 2020 - Wiley Online Library
Rapid improvements in medical technology, big data analysis, and molecular medicine
come with promises of revolutionizing medical care. They span the spectrum from …
come with promises of revolutionizing medical care. They span the spectrum from …