An update on the HIV DNA vaccine strategy

J Hokello, AL Sharma, M Tyagi - Vaccines, 2021 - mdpi.com
In 2020, the global prevalence of human immunodeficiency virus (HIV) infection was
estimated to be 38 million, and a total of 690,000 people died from acquired …

Interests of the non-human primate models for HIV cure research

G Terrade, N Huot, C Petitdemange, M Lazzerini… - Vaccines, 2021 - mdpi.com
Non-human primate (NHP) models are important for vaccine development and also
contribute to HIV cure research. Although none of the animal models are perfect, NHPs …

Effects of therapeutic vaccination on the control of SIV in rhesus macaques with variable responsiveness to antiretroviral drugs

HC Tunggal, PV Munson, MA O'Connor, N Hajari… - Plos one, 2021 - journals.plos.org
A therapeutic vaccine that induces lasting control of HIV infection could eliminate the need
for lifelong adherence to antiretroviral therapy. This study investigated a therapeutic DNA …

HIV reservoir: Antiviral immune responses and immune interventions for curing HIV infection

S Li, C Moog, T Zhang, B Su - Chinese Medical Journal, 2022 - mednexus.org
Antiretroviral therapy against human immunodeficiency virus (HIV) is effective in controlling
viral replication but cannot completely eliminate HIV due to the persistence of the HIV …

HTLV-1 Proliferation after CD8+ Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques

M Nakamura-Hoshi, T Nomura, M Nishizawa… - Microbiology …, 2023 - Am Soc Microbiol
HTLV-1 can cause serious diseases such as adult T-cell leukemia (ATL) in humans after
chronic asymptomatic latent infection with substantial proviral load. Proviruses are …

[图书][B] Characterizing the immunogenicity of a therapeutic DNA vaccine and determinants of viral control in SIV-infected rhesus macaques with variable responses to …

H Tunggal - 2021 - search.proquest.com
A therapeutic vaccine that induces lasting control of HIV infection could eliminate the need
for lifelong adherence to antiretroviral therapy. This study investigated a therapeutic DNA …

Vers une thérapie curative pour le VIH/SIDA‎: Panorama des stratégies étudiées et apports des modèles animaux

G Terrade - 2020 - oatao.univ-toulouse.fr
Près de quarante ans après l'émergence du VIH/SIDA, des progrès scientifiques et
thérapeutiques majeurs ont été obtenus. Toutefois, aucun traitement curatif n'est …