COPD immunopathology

G Caramori, P Casolari, A Barczyk, AL Durham… - Seminars in …, 2016 - Springer
The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …

Quantitative computed tomography measurements to evaluate airway disease in chronic obstructive pulmonary disease: relationship to physiological measurements …

A Nambu, J Zach, J Schroeder, G Jin, SS Kim… - European journal of …, 2016 - Elsevier
Purpose To correlate currently available quantitative CT measurements for airway disease
with physiological indices and the body-mass index, airflow obstruction, dyspnea, and …

Risk factors for impaired respiratory function post COVID‐19: A prospective cohort study of nonhospitalized and hospitalized patients

T Björsell, J Sundh, A Lange, C Ahlm… - Journal of Internal …, 2023 - Wiley Online Library
Background Severe COVID‐19 increases the risk for long‐term respiratory impairment, but
data after mild COVID‐19 are scarce. Our aims were to determine risk factors for reduced …

Association between emphysema-like lung on cardiac computed tomography and mortality in persons without airflow obstruction: a cohort study

EC Oelsner, EA Hoffman, AR Folsom… - Annals of internal …, 2014 - acpjournals.org
Background: Low lung function is known to predict mortality in the general population, but
the prognostic significance of emphysema on computed tomography (CT) in persons without …

Identification of COPD patients at high risk for lung cancer mortality using the COPD-LUCSS-DLCO

JP de-Torres, JM Marín, C Casanova, V Pinto-Plata… - Chest, 2016 - Elsevier
Background The COPD-Lung Cancer Screening Score (COPD-LUCSS) is a tool designed to
help identify patients with COPD with the highest risk of developing lung cancer (LC). The …

Diffusing capacity as an independent predictor of acute exacerbations in chronic obstructive pulmonary disease

H Park, HJ Lee, JK Lee, TY Park, KN Jin, EY Heo… - Scientific Reports, 2024 - nature.com
A weak correlation between diffusing capacity of the lung for carbon monoxide (DLCO) and
emphysema has been reported. This study investigated whether impaired DLCO in chronic …

Relationships between diffusing capacity for carbon monoxide (DLCO), and quantitative computed tomography measurements and visual assessment for chronic …

A Nambu, J Zach, J Schroeder, GY Jin, SS Kim… - European journal of …, 2015 - Elsevier
Purpose To evaluate the relationships between DL CO, and Quantitative CT (QCT)
measurements and visual assessment of pulmonary emphysema and to test the relative …

Novel functional imaging of changes in small airways of patients treated with extrafine beclomethasone/formoterol

W Vos, J De Backer, G Poli, A De Volder, L Ghys… - Respiration, 2013 - karger.com
Background: Inhaled formulations using extrafine particles of long-acting β2-agonists and
corticosteroids were developed to optimize asthma treatment. Findings that these …

Molecular pathogenesis of cigarette smoking–induced stable COPD

G Caramori, P Kirkham, A Barczyk… - Annals of the new …, 2015 - Wiley Online Library
Inflammation is a central feature of stable chronic obstructive pulmonary disease (COPD)
and involves both activation of structural cells of the airways and the lungs and the activation …

Relationship between diffusion capacity and small airway abnormality in COPDGene

RN Criner, CR Hatt, CJ Galbán, EA Kazerooni… - Respiratory …, 2019 - Springer
Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with
emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but …