Gray matter changes are thought to be closely related to cognitive decline in mild cognitive
impairment (MCI) patients. The study aimed to explore cortical and subcortical structural …

Purpose To investigate spontaneous brain activity in patients with dry eye (DE) and healthy
control (HC) using the fractional amplitude of low frequency fluctuation (fALFF) technique …

Background: The association between regional volumes and resting-state functional
networks was tested within the default-mode network (DMN), influenced by Alzheimer …

Brain aging leads to difficulties in functional independence. Mitigating these difficulties can
benefit from technology that predicts, monitors, and modifies brain aging. Translational …

The identification of abnormal cognitive decline at an early stage becomes an increasingly
significant conundrum to physicians and is of major interest in the studies of mild cognitive …

The disease roots of Alzheimer's disease (AD) are unknown. Functional connection (FC)
methodology based on functional MRI data is an effective lever to investigate macroscopic …

Alzheimer's disease (AD) is a common neurodegenerative brain disease, which seriously
affects the quality of life. Predicting its early stage (eg, mild cognitive impairment (MCI) and …

Background: Both late-life depression (LLD) and short sleep duration increase the risk of
cognitive impairment. Increased insular resting-state functional connectivity (FC) has been …

Alzheimer's disease (AD) is a common neurodegenerative disorder causing dementia in the
elderly population. Functional disconnection of brain is considered to be the main cause of …

Background: Depressive symptoms were thought to increase the risk of vascular dementia.
Previous studies reported widespread white matter damages in the subcortical vascular mild …